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N C Luetteke

Explore the profile of N C Luetteke including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 948
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11.
Sandgren E, Luetteke N, Qiu T, Palmiter R, Brinster R, Lee D
Mol Cell Biol . 1993 Jan; 13(1):320-30. PMID: 8417334
To characterize the effect(s) of transforming growth factor alpha (TGF alpha) during multistage carcinogenesis, we examined tumor development in pancreas and liver of transgenic mice that coexpressed TGF alpha with...
12.
Nelson K, Takahashi T, Lee D, Luetteke N, Bossert N, Ross K, et al.
Endocrinology . 1992 Oct; 131(4):1657-64. PMID: 1396310
To better understand the role of peptide growth factors in sex steroid hormone-mediated growth of the female reproductive tract, the effect of estrogen on the expression of transforming growth factor-alpha...
13.
Lee D, Luetteke N, Petch L
Cancer Treat Res . 1992 Jan; 63:233-54. PMID: 1363359
No abstract available.
14.
Blasband A, Gilligan D, Winchell L, Wong S, Luetteke N, ROGERS K, et al.
Oncogene . 1990 Aug; 5(8):1213-21. PMID: 2392325
TGF alpha is one member of a family of soluble growth factors that are derived from integral-membrane precursors. The mature form of TGF alpha is released from its transmembrane precursor...
15.
Luetteke N, Lee D
Semin Cancer Biol . 1990 Aug; 1(4):265-75. PMID: 2103501
Transforming growth factor alpha (TGF alpha) is a 6 kDa polypeptide mitogen that interacts with the epidermal growth factor receptor and activates its intrinsic tyrosine kinase. The mature 50 amino...
16.
Sandgren E, Luetteke N, Palmiter R, Brinster R, Lee D
Cell . 1990 Jun; 61(6):1121-35. PMID: 1693546
Metallothionein-directed expression of TGF alpha in transgenic mice induced a spectrum of changes in the growth and differentiation of certain adult tissues. First, TGF alpha promoted a uniform epithelial hyperplasia...
17.
Luetteke N, Michalopoulos G, Teixido J, Gilmore R, Massague J, Lee D
Biochemistry . 1988 Aug; 27(17):6487-94. PMID: 3219349
In addition to the mature 50 amino acid transforming growth factor alpha (TGF alpha), some transformed cells appear to produce multiple higher molecular weight forms. The structure and derivation of...
18.
Gebhardt R, Cruise J, Houck K, Luetteke N, Novotny A, Thaler F, et al.
Differentiation . 1986 Jan; 33(1):45-55. PMID: 2880778
In rat liver parenchyma, two subpopulations of hepatocytes can be distinguished by the absence or presence of the marker enzyme, glutamine synthetase (GS). Hepatocytes in the perivenous zone immediately adjacent...
19.
Luetteke N, Michalopoulos G
Cancer Res . 1985 Dec; 45(12 Pt 1):6331-7. PMID: 2998598
Serum-free medium conditioned by confluent cultures of JM1 of JM2 rat hepatocellular carcinoma cells stimulated DNA synthesis in primary cultures of adult rat hepatocytes in a dose-dependent, saturable manner and...