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G K Michalopoulos

Explore the profile of G K Michalopoulos including associated specialties, affiliations and a list of published articles. Areas
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Articles 99
Citations 3702
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Recent Articles
1.
Michalopoulos G
Methods Mol Med . 2011 Mar; 18:227-43. PMID: 21370180
Liver tissue has been used to study regeneration and carcinogenesis, as well as a whole array of liver-specific differentiated functions, including regulation and synthesis of blood proteins, coagulation factors, lipoproteins....
2.
Michalopoulos G, BOWEN W, Mule K, Stolz D
Am J Pathol . 2001 Nov; 159(5):1877-87. PMID: 11696448
Hepatocytes and other cellular elements isolated by collagenase perfusion of the liver and maintained in defined culture conditions undergo a series of complex changes, including apoptosis and cell proliferation, to...
3.
Pediaditakis P, Lopez-Talavera J, Petersen B, Monga S, Michalopoulos G
Hepatology . 2001 Oct; 34(4 Pt 1):688-93. PMID: 11584364
Hepatocyte growth factor/scatter factor (HGF/SF) is a pluripotent growth factor capable of acting as a motogen, a morphogen, and a mitogen. Originally, HGF/SF was found as a blood-borne mitogen for...
4.
Monga S, Pediaditakis P, Mule K, Stolz D, Michalopoulos G
Hepatology . 2001 May; 33(5):1098-109. PMID: 11343237
The wnt/beta-catenin pathway is important during embryogenesis and carcinogenesis. beta-Catenin interaction with E-cadherin has been shown to be crucial in cell-cell adhesion. We report novel findings in the wnt pathway...
5.
Yang J, Chen S, Huang L, Michalopoulos G, Liu Y
Hepatology . 2001 Apr; 33(4):848-59. PMID: 11283849
To understand the physiological functions of exogenous hepatocyte growth factor (HGF) on normal adult animals, we delivered human HGF gene into mice by a hydrodynamics-based in vivo gene transfection approach...
6.
Rao U, Gollin S, Beaves S, Cieply K, Nalesnik M, Michalopoulos G
Mol Diagn . 2001 Mar; 6(1):27-37. PMID: 11257209
Background: Proto-oncogene MYC, mapped to chromosomal band 8q24 and the genes for hepatocyte growth factor (HGF at 7q21) and its receptor, MET, at chromosomal band 7q31, have an important role...
7.
Runge D, Michalopoulos G, Strom S, Runge D
Biochem Biophys Res Commun . 2000 Jul; 274(1):1-3. PMID: 10903886
No abstract available.
8.
Runge D, Kohler C, Kostrubsky V, Jager D, Lehmann T, Runge D, et al.
Biochem Biophys Res Commun . 2000 Jun; 273(1):333-41. PMID: 10873607
Human hepatocytes cultured serum-free for up to 6 weeks were used to study expression and induction of enzymes and membrane transport proteins involved in drug metabolism. Phase I drug metabolizing...
9.
Runge D, Fleig W, Michalopoulos G, Strom S, Runge D
Dtsch Med Wochenschr . 2000 Apr; 125(13):397-400. PMID: 10778401
No abstract available.
10.
Jo M, Stolz D, Esplen J, Dorko K, Michalopoulos G, Strom S
J Biol Chem . 2000 Mar; 275(12):8806-11. PMID: 10722725
In rat liver epithelial cells constitutively expressing transforming growth factor alpha (TGFalpha), c-Met is constitutively phosphorylated in the absence of its ligand, hepatocyte growth factor. We proposed that TGFalpha and...