E P Sandgren
Overview
Explore the profile of E P Sandgren including associated specialties, affiliations and a list of published articles.
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Articles
41
Citations
1642
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Recent Articles
1.
Rose-Hellekant T, Schroeder M, Brockman J, Zhdankin O, Bolstad R, Chen K, et al.
Oncogene
. 2007 Mar;
26(36):5238-46.
PMID: 17334393
We characterized the novel NRL-transforming growth factor alpha (NRL-TGFalpha) transgenic mouse model in which growth factor - steroid receptor interactions were explored. The NRL promoter directs transgene expression to mammary...
2.
Schroeder M, Rose-Hellekant T, Sandgren E, Schuler L
Mol Cell Endocrinol
. 2001 Apr;
175(1-2):173-83.
PMID: 11325527
Mammary TGFalpha overexpression results in delayed involution and eventually mammary cancer in transgenic mice. We hypothesized that STATs and PRL receptors (PRLR), critical regulators of mammary function, are altered in...
3.
Kim S, Zeller K, Dang C, Sandgren E, Lee L
Anal Biochem
. 2001 Jan;
288(2):141-148.
PMID: 11152584
Representational difference analysis (RDA) combined with cDNA arrays is an effective approach to identify differentially expressed genes. To identify differentially expressed genes in c-Myc transgenic mouse liver, we compared the...
4.
Weglarz T, Degen J, Sandgren E
Am J Pathol
. 2000 Dec;
157(6):1963-74.
PMID: 11106569
To examine the process of liver repopulation by transplanted hepatocytes, we developed transgenic mice carrying a mouse major urinary protein-urokinase-type plasminogen activator fusion transgene. Expression of this transgene induced diffuse...
5.
Weglarz T, Sandgren E
Proc Natl Acad Sci U S A
. 2000 Oct;
97(23):12595-600.
PMID: 11050176
After surgical removal of two-thirds of the liver, remaining hepatocytes replicate and restore hepatic mass within 2 weeks. This process must be initiated by signals extrinsic to the hepatocyte, but...
6.
Grippo P, Sandgren E
Am J Pathol
. 2000 Sep;
157(3):805-13.
PMID: 10980120
Transitional cell carcinoma (TCC), a neoplasm of urinary bladder urothelial cells, generally appears in either of two forms, papillary non-invasive or invasive TCC, although intermediate forms can occur. Each has...
7.
Braun K, Sandgren E
Am J Pathol
. 2000 Aug;
157(2):561-9.
PMID: 10934158
Several treatments in rodents, including administration of the alkylating agent dipin, followed by two-thirds partial hepatectomy in mice combine destruction of liver parenchyma with hepatocyte mitoinhibition. These treatments induce proliferation...
8.
Rose-Hellekant T, Sandgren E
Oncogene
. 2000 Mar;
19(8):1092-6.
PMID: 10713695
The growth factor transforming growth factor alpha (TGFalpha) and the nuclear transcription factor c-myc often are overexpressed by human breast cancer cells. To produce models of breast disease with these...
9.
Braun K, Degen J, Sandgren E
Nat Med
. 2000 Mar;
6(3):320-6.
PMID: 10700235
To provide long-term therapy in patients with severe toxin-induced hepatic parenchymal damage, donor hepatocytes would need to replicate and replace a large portion of the damaged parenchyma. Using a mouse...
10.
Herschman H, MacLaren D, Iyer M, Namavari M, Bobinski K, Green L, et al.
J Neurosci Res
. 2000 Mar;
59(6):699-705.
PMID: 10700006
The ability to monitor reporter gene expression in living animals and in patients will permit longitudinal examinations both of somatically transferred DNA in experimental animals and patients and of transgenic...