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Monique A M Willart

Explore the profile of Monique A M Willart including associated specialties, affiliations and a list of published articles. Areas
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Citations 2373
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Recent Articles
1.
Willart M, Poulliot P, Lambrecht B, Kool M
Methods Mol Biol . 2013 Aug; 1032:185-204. PMID: 23943454
Sensitization of mice to real-life allergens or harmless antigen with the use of adjuvants will lead to the induction of DAMPs in the immune system. We have shown that the...
2.
Willart M, Deswarte K, Pouliot P, Braun H, Beyaert R, Lambrecht B, et al.
J Exp Med . 2012 Jul; 209(8):1505-17. PMID: 22802353
House dust mite (HDM) is one of the most common allergens worldwide. In this study, we have addressed the involvement of IL-1 in the interaction between HDM and the innate...
3.
Kool M, Willart M, van Nimwegen M, Bergen I, Pouliot P, Virchow J, et al.
Immunity . 2011 Apr; 34(4):527-40. PMID: 21474346
Although deposition of uric acid (UA) crystals is known as the cause of gout, it is unclear whether UA plays a role in other inflammatory diseases. We here have shown...
4.
Hammad H, Plantinga M, Deswarte K, Pouliot P, Willart M, Kool M, et al.
J Exp Med . 2010 Sep; 207(10):2097-111. PMID: 20819925
It is unclear how Th2 immunity is induced in response to allergens like house dust mite (HDM). Here, we show that HDM inhalation leads to the TLR4/MyD88-dependent recruitment of IL-4...
5.
Willart M, Hammad H
Allergol Int . 2010 Feb; 59(2):95-103. PMID: 20179415
Allergic patients mount a Th2 response to common allergens, like house dust mite (HDM), pollens, molds and animal dander. Most inhaled antigens are immunologically inert, however if these antigens are...
6.
Provoost S, Maes T, Willart M, Joos G, Lambrecht B, Tournoy K
J Immunol . 2009 Dec; 184(1):426-32. PMID: 19949085
Particulate matter, such as diesel exhaust particles (DEPs), modulate adaptive immune responses in the lung; however, their mechanism of action remains largely unclear. Pulmonary dendritic cells (DCs) are crucial mediators...
7.
Willart M, Jan de Heer H, Hammad H, Soullie T, Deswarte K, Clausen B, et al.
J Exp Med . 2009 Oct; 206(12):2823-35. PMID: 19858325
The bloodstream is an important route of dissemination of invading pathogens. Most of the small bloodborne pathogens, like bacteria or viruses, are filtered by the spleen or liver sinusoids and...
8.
GeurtsvanKessel C, Willart M, Bergen I, van Rijt L, Muskens F, Elewaut D, et al.
J Exp Med . 2009 Oct; 206(11):2339-49. PMID: 19808255
Tertiary lymphoid organs (TLOs) are organized aggregates of B and T cells formed in postembryonic life in response to chronic immune responses to infectious agents or self-antigens. Although CD11c+ dendritic...
9.
Kool M, van Nimwegen M, Willart M, Muskens F, Boon L, Smit J, et al.
J Immunol . 2009 Jun; 183(2):1074-82. PMID: 19553531
It was previously shown that administration of recombinant human Fms-like tyrosine kinase receptor-3 ligand (Flt3L) before allergen challenge of sensitized mice suppresses the cardinal features of asthma through unclear mechanisms....
10.
Lambrecht B, Kool M, Willart M, Hammad H
Curr Opin Immunol . 2009 Feb; 21(1):23-9. PMID: 19246182
Aluminum-containing adjuvants continue to be the most widely used adjuvants for human use. In the last year a major breakthrough has been the realization that alum adjuvant triggers an ancient...