Bjorn E Clausen
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Explore the profile of Bjorn E Clausen including associated specialties, affiliations and a list of published articles.
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117
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6222
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Recent Articles
1.
Narasimhan H, Richter M, Shakiba R, Papaioannou N, Stehle C, Ravi Rengarajan K, et al.
Proc Natl Acad Sci U S A
. 2025 Feb;
122(9):e2417308122.
PMID: 39993193
Conventional dendritic cells (cDCs) are potent antigen-presenting cells (APCs) that integrate signals from their environment allowing them to direct situation-adapted immunity. Thereby they harbor great potential for being targeted in...
2.
Backer R, Probst H, Clausen B
Vaccines (Basel)
. 2024 Nov;
12(11).
PMID: 39591196
Dendritic cells (DCs) are present in almost all tissues, where they act as sentinels involved in innate recognition and the initiation of adaptive immune responses. The DC family consists of...
3.
Raquer-McKay H, Maqueda-Alfaro R, Saravanan S, Arroyo Hornero R, Clausen B, Gottfried-Blackmore A, et al.
Proc Natl Acad Sci U S A
. 2024 Nov;
121(47):e2404927121.
PMID: 39541348
Current evidence suggests that ontogeny may account for the functional heterogeneity of some tissue macrophages, but not others. Here, we asked whether developmental origin drives different functions of skin Langerhans...
4.
Arbogast F, Sal-Carro R, Boufenghour W, Frenger Q, Bouis D, Filippi De La Palavesa L, et al.
J Cell Biol
. 2024 Nov;
224(2).
PMID: 39535446
Macroautophagy (often-named autophagy), a catabolic process involving autophagy-related (Atg) genes, prevents the accumulation of harmful cytoplasmic components and mobilizes energy reserves in long-lived and self-renewing cells. Autophagy deficiency affects antigen...
5.
Fu C, Wang J, Ma T, Yin C, Zhou L, Clausen B, et al.
Vaccines (Basel)
. 2024 Sep;
12(9).
PMID: 39340067
GSK-3β plays a critical role in regulating the Wnt/β-catenin signaling pathway, and manipulating GSK-3β in dendritic cells (DCs) has been shown to improve the antitumor efficacy of DC vaccines. Since...
6.
Fu C, Wang J, Ma T, Yin C, Zhou L, Clausen B, et al.
Vaccines (Basel)
. 2024 May;
12(5).
PMID: 38793711
Recent studies have demonstrated that β-catenin in dendritic cells (DCs) serves as a key mediator in promoting both CD4 and CD8 T cell tolerance, although the mechanisms underlying how β-catenin...
7.
Eich C, Vogt J, Langst V, Clausen B, Hovelmeyer N
Front Immunol
. 2024 Mar;
15:1295863.
PMID: 38500875
Colorectal cancer (CRC) is a complex and heterogeneous disease characterized by dysregulated interactions between tumor cells and the immune system. The tumor microenvironment plays a pivotal role in cancer initiation...
8.
Kamenjarin N, Hodapp K, Melchior F, Harms G, Hartmann A, Bartneck J, et al.
Proc Natl Acad Sci U S A
. 2023 Aug;
120(34):e2219932120.
PMID: 37579158
Tissue-resident memory CD8 T cells (T) reside at sites of previous infection, providing protection against reinfection with the same pathogen. In the skin, T patrol the epidermis, where keratinocytes are...
9.
Kramer E, Tzetzo S, Colligan S, Hensen M, Brackett C, Clausen B, et al.
JCI Insight
. 2023 Apr;
8(8).
PMID: 37092550
The main cause of malignancy-related mortality is metastasis. Although metastatic progression is driven by diverse tumor-intrinsic mechanisms, there is a growing appreciation for the contribution of tumor-extrinsic elements of the...
10.
Yeh C, Su S, Tan Y, Tsai T, Liang P, Kelel M, et al.
J Invest Dermatol
. 2023 Mar;
143(8):1449-1460.
PMID: 36868499
Psoriasis is an IL-23/IL-17-mediated inflammatory autoimmune dermatosis, and UVB may contribute to immunosuppression and ameliorate associated symptoms. One of the pathophysiology underlying UVB therapy is the production of cis-urocanic acid...