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Mogens Kruhoffer

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Articles 63
Citations 2708
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Recent Articles
21.
Knudsen A, Kannerup A, Dich R, Kruhoffer M, Funch-Jensen P, Gronbaek H, et al.
HPB (Oxford) . 2010 Oct; 12(8):554-60. PMID: 20887323
Background: During surgery, ischaemic pre- (IPC) and post-conditioning (IPO) protects the liver against ischaemia/reperfusion injuries (I/R-injuries). The impact of ischaemic conditioning on liver regeneration has been less well studied. Angiogenesis...
22.
Nielsen K, Kruhoffer M, Holm I, Jorgensen A, Nielsen A
BMC Res Notes . 2010 May; 3:127. PMID: 20444278
Background: Mammalian evolution is characterized by a progressive expansion of the surface area of the cerebral cortex, an increase that is accompanied by gyration of the cortical surface. The mechanisms...
23.
Jorissen R, Gibbs P, Christie M, Prakash S, Lipton L, Desai J, et al.
Clin Cancer Res . 2009 Dec; 15(24):7642-7651. PMID: 19996206
PURPOSE: Colorectal cancer prognosis is currently predicted from pathologic staging, providing limited discrimination for Dukes stage B and C disease. Additional markers for outcome are required to help guide therapy...
24.
Berchtold L, Larsen C, Vaag A, Faulenbach M, Workman C, Kruhoffer M, et al.
Eur Cytokine Netw . 2009 Jun; 20(2):81-7. PMID: 19541594
Background: We have previously reported that systemic blockade of IL-1beta in patients with type 2 diabetes with anakinra (a recombinant human interleukin-1-receptor antagonist, IL-1Ra), lowered glycated hemoglobin improved beta-cell function...
25.
Birkenkamp-Demtroder K, Mansilla F, Sorensen F, Kruhoffer M, Cabezon T, Christensen L, et al.
Mol Oncol . 2009 Apr; 1(2):181-95. PMID: 19383294
Transcript profiling of 27 normal colon mucosas and 258 adenocarcinomas showed Keratin23 to be increased in 78% microsatellite-stable tumors, while microsatellite-instable tumors showed low transcript levels, comparable to normal mucosas....
26.
Jensen S, Vainer B, Kruhoffer M, Sorensen J
BMC Cancer . 2009 Jan; 9:25. PMID: 19154585
Background: Microsatellite instability (MSI) refers to mutations in short motifs of tandemly repeated nucleotides resulting from replication errors and deficient mismatch repair (MMR). Colorectal cancer with MSI has characteristic biology...
27.
Jorissen R, Lipton L, Gibbs P, Chapman M, Desai J, Jones I, et al.
Clin Cancer Res . 2008 Dec; 14(24):8061-9. PMID: 19088021
Purpose: About 15% of colorectal cancers harbor microsatellite instability (MSI). MSI-associated gene expression changes have been identified in colorectal cancers, but little overlap exists between signatures hindering an assessment of...
28.
Mansilla F, da Costa K, Wang S, Kruhoffer M, Lewin T, Orntoft T, et al.
J Mol Med (Berl) . 2008 Nov; 87(1):85-97. PMID: 18974965
The alteration of the choline metabolite profile is a well-established characteristic of cancer cells. In colorectal cancer (CRC), phosphatidylcholine is the most prominent phospholipid. In the present study, we report...
29.
Schepeler T, Reinert J, Ostenfeld M, Christensen L, Silahtaroglu A, Dyrskjot L, et al.
Cancer Res . 2008 Aug; 68(15):6416-24. PMID: 18676867
MicroRNAs (miRNA) are a class of small noncoding RNAs with important posttranscriptional regulatory functions. Recent data suggest that miRNAs are aberrantly expressed in many human cancers and that they may...
30.
Strom C, Kruhoffer M, Knudsen S, Stensgaard-Hansen F, Jonassen T, Orntoft T, et al.
Comp Funct Genomics . 2008 Jul; 5(6-7):459-70. PMID: 18629135
Although the molecular signals underlying cardiac hypertrophy have been the subject of intense investigation, the extent of common and distinct gene regulation between different forms of cardiac hypertrophy remains unclear....