Lauri A Aaltonen
Overview
Explore the profile of Lauri A Aaltonen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
213
Citations
9739
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Jokinen V, Taira A, Kolterud A, Ahlgren I, Palin K, Katainen R, et al.
BJC Rep
. 2025 Feb;
3(1):9.
PMID: 40016412
Background: Fibroblast growth factor 1-4 (FGFR1-4) are well-known oncogenic drivers in many cancer types. Here, we studied the role of FGFRs in uterine leiomyoma (UL) that is a benign neoplasm...
2.
Maklin T, Taira A, Arredondo-Alonso S, Shao Y, Stratton M, Lawley T, et al.
Lancet Microbe
. 2024 Dec;
:101015.
PMID: 39644909
Biomedical research has implicated the bacterial metabolite colibactin as a causal risk factor for several cancer types, in particular, colorectal cancer. Colibactin has been known to drive tumorigenesis by inducing...
3.
Sipila L, Tanskanen T, Heikkinen S, Seppa K, Aavikko M, Ravantti J, et al.
Acta Oncol
. 2024 Nov;
63:841-849.
PMID: 39492803
Background And Purpose: Many non-neoplastic diseases have been established to be tumorigenic, and cancers are sometimes misdiagnosed as non-neoplastic diseases. We conducted a comprehensive registry-based study of site-specific cancer diagnosis...
4.
Martin S, Katainen R, Taira A, Valimaki N, Ristimaki A, Seppala T, et al.
Hum Mol Genet
. 2024 Aug;
33(21):1858-1872.
PMID: 39180486
Microsatellite unstable colorectal cancer (MSI-CRC) can arise through germline mutations in mismatch repair (MMR) genes in individuals with Lynch syndrome (LS), or sporadically through promoter methylation of the MMR gene...
5.
Verhagen M, Joosten R, Schmitt M, Valimaki N, Sacchetti A, Rajamaki K, et al.
Nat Genet
. 2024 Jun;
56(7):1456-1467.
PMID: 38902475
According to conventional views, colon cancer originates from stem cells. However, inflammation, a key risk factor for colon cancer, has been shown to suppress intestinal stemness. Here, we used Paneth...
6.
Sipila L, Aavikko M, Ravantti J, Martin S, Kuopio T, Lahtinen L, et al.
Fam Cancer
. 2024 Jun;
23(4):647-652.
PMID: 38847920
Some 50% of Finnish Lynch Syndrome (LS) cases are caused by a founder variant in MLH1, in which the entire exon 16 has been lost due to an Alu-mediated recombination...
7.
Nurminen R, Afyounian E, Paunu N, Katainen R, Isomaki M, Nurminen A, et al.
Sci Rep
. 2024 May;
14(1):11562.
PMID: 38773237
Predisposing factors underlying familial aggregation of non-syndromic gliomas are still to be uncovered. Whole-exome sequencing was performed in four Finnish families with brain tumors to identify rare predisposing variants. A...
8.
Sipila L, Katainen R, Aavikko M, Ravantti J, Donner I, Lehtonen R, et al.
Genes Environ
. 2024 May;
46(1):12.
PMID: 38711096
Background: Sinonasal adenocarcinoma is a rare cancer, encompassing two different entities, the intestinal-type sinonasal adenocarcinoma (ITAC) and the non-intestinal-type sinonasal adenocarcinoma (non-ITAC). Occurrence of ITAC is strongly associated with exposure...
9.
Chen Z, Guo X, Tao R, Huyghe J, Law P, Fernandez-Rozadilla C, et al.
Nat Commun
. 2024 Apr;
15(1):3557.
PMID: 38670944
Genome-wide association studies (GWAS) have identified more than 200 common genetic variants independently associated with colorectal cancer (CRC) risk, but the causal variants and target genes are mostly unknown. We...
10.
Lagana A, Romano A, Vanhie A, Bafort C, Gotte M, Aaltonen L, et al.
Gynecol Obstet Invest
. 2024 Feb;
89(2):73-86.
PMID: 38382486
Background: Uterine fibroids are benign monoclonal tumors originating from the smooth muscle cells of the myometrium, constituting the most prevalent pathology within the female genital tract. Uterine sarcomas, although rare,...