Mogens Kruhoffer
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Explore the profile of Mogens Kruhoffer including associated specialties, affiliations and a list of published articles.
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63
Citations
2708
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Recent Articles
11.
Hedegaard J, Thorsen K, Lund M, Hein A, Hamilton-Dutoit S, Vang S, et al.
PLoS One
. 2014 Jun;
9(5):e98187.
PMID: 24878701
Formalin-fixed, paraffin-embedded (FFPE) tissues are an invaluable resource for clinical research. However, nucleic acids extracted from FFPE tissues are fragmented and chemically modified making them challenging to use in molecular...
12.
Mortensen L, Bech B, Nohr E, Kruhoffer M, Kjaergaard S, Uldbjerg N, et al.
Int J Epidemiol
. 2014 Jan;
42(6):1697-701.
PMID: 24415608
Exposure during fetal life may have long-lasting health consequences for the child. Cohorts with biological material are necessary to investigate the possible biological mechanisms behind this potential early programming of...
13.
Pedersen J, Fredsoe J, Roedgaard M, Andreasen L, Mundbjerg K, Kruhoffer M, et al.
PLoS Genet
. 2013 Jan;
8(12):e1003128.
PMID: 23284296
To investigate the role of DNA topoisomerases in transcription, we have studied global gene expression in Saccharomyces cerevisiae cells deficient for topoisomerases I and II and performed single-gene analyses to...
14.
Schultz N, Roslind A, Christensen I, Horn T, Hogdall E, Pedersen L, et al.
Pancreas
. 2012 Jun;
41(5):759-66.
PMID: 22699145
Objectives: The frequencies and prognostic role of KRAS and BRAF mutations in patients operated on for pancreatic ductal adenocarcinomas (PDACs) and ampullary adenocarcinomas (A-ACs) are scantily studied. Methods: KRAS and...
15.
Knudsen A, Kannerup A, Dich R, Funch-Jensen P, Gronbaek H, Kruhoffer M, et al.
Am J Physiol Gastrointest Liver Physiol
. 2012 Jun;
303(4):G482-9.
PMID: 22679003
Ischemic pre (IPC)- and postconditioning (IPO) protect the liver against ischemia/reperfusion injuries (IRI). Conditioning involves several different trigger factors, mediators, and effectors, many of which are affected during the early...
16.
Bertini I, Cacciatore S, Jensen B, Schou J, Johansen J, Kruhoffer M, et al.
Cancer Res
. 2011 Nov;
72(1):356-64.
PMID: 22080567
Earlier detection of patients with metastatic colorectal cancer (mCRC) might improve their treatment and survival outcomes. In this study, we used proton nuclear magnetic resonance ((1)H-NMR) to profile the serum...
17.
Liaset B, Hao Q, Jorgensen H, Hallenborg P, Du Z, Ma T, et al.
J Biol Chem
. 2011 Jun;
286(32):28382-95.
PMID: 21680746
Bile acids (BAs) are powerful regulators of metabolism, and mice treated orally with cholic acid are protected from diet-induced obesity, hepatic lipid accumulation, and increased plasma triacylglycerol (TAG) and glucose...
18.
Baandrup J, Markvardsen L, Peters C, Schou U, Jensen J, Magnusson N, et al.
PLoS One
. 2011 Jan;
6(1):e15859.
PMID: 21246034
Background: The present study investigated whether changes in gene expression in the right ventricle following pulmonary hypertension can be attributed to hypoxia or pressure loading. Methodology/principal Findings: To distinguish hypoxia...
19.
Neess D, Bloksgaard M, Bek S, Marcher A, Elle I, Helledie T, et al.
J Biol Chem
. 2010 Nov;
286(5):3460-72.
PMID: 21106527
The acyl-CoA-binding protein (ACBP)/diazepam binding inhibitor is an intracellular protein that binds C(14)-C(22) acyl-CoA esters and is thought to act as an acyl-CoA transporter. In vitro analyses have indicated that...
20.
Marteau J, Rigaud O, Brugat T, Gault N, Vallat L, Kruhoffer M, et al.
BMC Med Genomics
. 2010 Nov;
3:53.
PMID: 21062507
Background: The sensitivity of chronic lymphocytic leukemia (CLL) cells to current treatments, both in vitro and in vivo, relies on their ability to activate apoptotic death. CLL cells resistant to...