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Michel Bouvier

Explore the profile of Michel Bouvier including associated specialties, affiliations and a list of published articles. Areas
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Articles 267
Citations 9812
Followers 0
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Recent Articles
1.
Sokolina K, Kittanakom S, Snider J, Kotlyar M, Maurice P, Gandia J, et al.
Mol Syst Biol . 2025 Jan; 21(2):208-209. PMID: 39762653
No abstract available.
2.
Borsdorf S, Zeug A, Wu Y, Mitroshina E, Vedunova M, Gaitonde S, et al.
Cell Commun Signal . 2024 Nov; 22(1):563. PMID: 39580460
Background: Homo- and heteromerization of G protein-coupled receptors (GPCRs) plays an important role in the regulation of receptor functions. Recently, we demonstrated an interaction between the serotonin receptor 7 (5-HT7R),...
3.
Jallouli R, Moreno Salinas A, Laniel A, Holleran B, Avet C, Jacob J, et al.
Res Sq . 2024 Sep; PMID: 39281883
GPR56, an adhesion G-protein coupled receptor (aGPCRs) with constitutive and ligand-promoted activity, is involved in many physiological and pathological processes. Whether the receptor's constitutive or ligand-promoted activation occur through the...
4.
Jallouli R, Moreno-Salinas A, Laniel A, Holleran B, Avet C, Jacob J, et al.
Cell Mol Life Sci . 2024 Sep; 81(1):383. PMID: 39231834
GPR56, an adhesion G-protein coupled receptor (aGPCRs) with constitutive and ligand-promoted activity, is involved in many physiological and pathological processes. Whether the receptor's constitutive or ligand-promoted activation occur through the...
5.
Rodriguez-Sarmiento D, Rondon-Villarreal P, Scarpelli-Pereira P, Bouvier M
Biomolecules . 2024 Aug; 14(8). PMID: 39199311
Kisspeptin, a key neuropeptide derived from the gene, is renowned for its critical role in regulating the hypothalamic-pituitary-gonadal axis and reproductive hormone secretion. Beyond its primary function in reproductive biology,...
6.
Sokrat B, Nguyen A, Thomsen A, Huang L, Kobayashi H, Kahsai A, et al.
Commun Biol . 2024 Jul; 7(1):826. PMID: 38972875
Classically, G protein-coupled receptors (GPCRs) promote signaling at the plasma membrane through activation of heterotrimeric Gαβγ proteins, followed by the recruitment of GPCR kinases and βarrestin (βarr) to initiate receptor...
7.
Wright S, Avet C, Gaitonde S, Muneta-Arrate I, Le Gouill C, Hogue M, et al.
Sci Signal . 2024 Jun; 17(841):eadi4747. PMID: 38889226
G protein-coupled receptors (GPCRs) regulate cellular signaling processes by coupling to diverse combinations of heterotrimeric G proteins composed of Gα, Gβ, and Gγ subunits. Biosensors based on bioluminescence resonance energy...
8.
Kossatz E, Diez-Alarcia R, Gaitonde S, Ramon-Duaso C, Stepniewski T, Aranda-Garcia D, et al.
Nat Commun . 2024 May; 15(1):4307. PMID: 38811567
G protein-coupled receptors (GPCRs) are sophisticated signaling machines able to simultaneously elicit multiple intracellular signaling pathways upon activation. Complete (in)activation of all pathways can be counterproductive for specific therapeutic applications....
9.
Gaitonde S, Avet C, de la Fuente Revenga M, Blondel-Tepaz E, Shahraki A, Pastor A, et al.
Mol Psychiatry . 2024 Apr; 29(9):2753-2764. PMID: 38561467
The intricate involvement of the serotonin 5-HT receptor (5-HTR) both in schizophrenia and in the activity of antipsychotic drugs is widely acknowledged. The currently marketed antipsychotic drugs, although effective in...
10.
Gross F, Mancini A, Breton B, Kobayashi H, Pereira P, Le Gouill C, et al.
Commun Biol . 2024 Mar; 7(1):250. PMID: 38429428
Mutations of receptor tyrosine kinases (RTKs) are associated with the development of many cancers by modifying receptor signaling and contributing to drug resistance in clinical settings. We present enhanced bystander...