Maximilian Billmann
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Explore the profile of Maximilian Billmann including associated specialties, affiliations and a list of published articles.
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25
Citations
1229
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Recent Articles
21.
Billmann M, Boutros M
Methods Mol Biol
. 2016 Oct;
1478:95-116.
PMID: 27730577
RNA interference (RNAi) is a potent tool for perturbation of gene function in model organisms and human cells. In Drosophila, efficient RNAi enables screening approaches for components of cellular processes...
22.
Costanzo M, VanderSluis B, Koch E, Baryshnikova A, Pons C, Tan G, et al.
Science
. 2016 Oct;
353(6306).
PMID: 27708008
We generated a global genetic interaction network for Saccharomyces cerevisiae, constructing more than 23 million double mutants, identifying about 550,000 negative and about 350,000 positive genetic interactions. This comprehensive network...
23.
Billmann M, Horn T, Fischer B, Sandmann T, Huber W, Boutros M
Mol Biol Cell
. 2016 Feb;
27(8):1397-407.
PMID: 26912791
Cell-based RNA interference (RNAi) is a powerful approach to screen for modulators of many cellular processes. However, resulting candidate gene lists from cell-based assays comprise diverse effectors, both direct and...
24.
Fischer B, Sandmann T, Horn T, Billmann M, Chaudhary V, Huber W, et al.
Elife
. 2015 Mar;
4.
PMID: 25748138
Gene-gene interactions shape complex phenotypes and modify the effects of mutations during development and disease. The effects of statistical gene-gene interactions on phenotypes have been used to assign genes to...
25.
Laufer C, Fischer B, Billmann M, Huber W, Boutros M
Nat Methods
. 2013 Apr;
10(5):427-31.
PMID: 23563794
Genetic interactions influence many phenotypes and can be used as a powerful experimental tool to discover functional relationships between genes. Here we describe a robust and scalable method to systematically...