Maximilian Billmann
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Explore the profile of Maximilian Billmann including associated specialties, affiliations and a list of published articles.
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25
Citations
1229
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Recent Articles
11.
Chan K, Farias A, Lee H, Guvenc F, Mero P, Brown K, et al.
Heliyon
. 2023 Jan;
9(1):e12744.
PMID: 36597481
SARS-CoV-2 depends on host cell components for infection and replication. Identification of virus-host dependencies offers an effective way to elucidate mechanisms involved in viral infection and replication. If druggable, host...
12.
Magtanong L, Mueller G, Williams K, Billmann M, Chan K, Armenta D, et al.
Cell Chem Biol
. 2022 Oct;
29(10):1568.
PMID: 36270234
No abstract available.
13.
Magtanong L, Mueller G, Williams K, Billmann M, Chan K, Armenta D, et al.
Cell Chem Biol
. 2022 Jul;
29(9):1409-1418.e6.
PMID: 35809566
Ferroptosis is an important mediator of pathophysiological cell death and an emerging target for cancer therapy. Whether ferroptosis sensitivity is governed by a single regulatory mechanism is unclear. Here, based...
14.
Ward H, Aregger M, Gonatopoulos-Pournatzis T, Billmann M, Ohsumi T, Brown K, et al.
Nat Protoc
. 2021 Sep;
16(10):4766-4798.
PMID: 34508259
The continued improvement of combinatorial CRISPR screening platforms necessitates the development of new computational pipelines for scoring combinatorial screening data. Unlike for single-guide RNA (sgRNA) pooled screening platforms, combinatorial scoring...
15.
Rahman M, Billmann M, Costanzo M, Aregger M, Tong A, Chan K, et al.
Mol Syst Biol
. 2021 May;
17(5):e10013.
PMID: 34018332
We present FLEX (Functional evaluation of experimental perturbations), a pipeline that leverages several functional annotation resources to establish reference standards for benchmarking human genome-wide CRISPR screen data and methods for...
16.
Gonatopoulos-Pournatzis T, Aregger M, Brown K, Farhangmehr S, Braunschweig U, Ward H, et al.
Nat Biotechnol
. 2020 Apr;
38(5):638-648.
PMID: 32249828
Systematic mapping of genetic interactions (GIs) and interrogation of the functions of sizable genomic segments in mammalian cells represent important goals of biomedical research. To advance these goals, we present...
17.
VanderSluis B, Costanzo M, Billmann M, Ward H, Myers C, Andrews B, et al.
Curr Opin Microbiol
. 2018 Jul;
45:170-179.
PMID: 30059827
Systematic experimental approaches have led to construction of comprehensive genetic and protein-protein interaction networks for the budding yeast, Saccharomyces cerevisiae. Genetic interactions capture functional relationships between genes using phenotypic readouts,...
18.
Billmann M, Chaudhary V, ElMaghraby M, Fischer B, Boutros M
Cell Syst
. 2017 Dec;
6(1):52-64.e4.
PMID: 29199019
Cellular signaling networks coordinate physiological processes in all multicellular organisms. Within networks, modules switch their function to control signaling activity in response to the cellular context. However, systematic approaches to...
19.
Hart T, Tong A, Chan K, van Leeuwen J, Seetharaman A, Aregger M, et al.
G3 (Bethesda)
. 2017 Jun;
7(8):2719-2727.
PMID: 28655737
The adaptation of CRISPR/SpCas9 technology to mammalian cell lines is transforming the study of human functional genomics. Pooled libraries of CRISPR guide RNAs (gRNAs) targeting human protein-coding genes and encoded...
20.
Billmann M, Boutros M
Cell Div
. 2017 Jan;
12:2.
PMID: 28077953
Genetic screens have identified many novel components of various biological processes, such as components required for cell cycle and cell division. While forward genetic screens typically generate unstructured 'hit' lists,...