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Mauro V de Almeida

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Citations 207
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Recent Articles
21.
Alves C, da Costa C, De Castro S, Correa T, Santiago G, Diniz R, et al.
Med Chem . 2012 Oct; 9(6):812-8. PMID: 23072554
Mitoxantrone is an anthracene-based anticancer agent whose efficacy in treating autoimmune diseases is believed to be due to cytotoxicity and inhibition of proliferation of cells. Several novel anthraquinone derivatives, analogs...
22.
de Almeida M, Couri M, Vitor de Assis J, Anconi C, Dos Santos H, De Almeida W
Magn Reson Chem . 2012 Aug; 50(9):608-14. PMID: 22865668
Density functional theory (DFT) calculations of (1) H NMR chemical shifts for l-quebrachitol isomers were performed using the B3LYP functional employing the 6-31G(d,p) and 6-311 + G(2d,p) basis sets. The...
23.
de Assis J, Teixeira M, Soares C, Lopes J, Carvalho G, Lourenco M, et al.
Eur J Pharm Sci . 2012 Jul; 47(3):539-48. PMID: 22841846
In this work the inclusion complex formation of isoniazid with sodium p-sulfonatocalix[n]arenes is reported aiming to improve the physicochemical and biopharmaceutical properties of isoniazid a first line antibuberculosis drug. The...
24.
Mazzoccoli L, Cadoso S, Amarante G, de Souza M, Domingues R, Machado M, et al.
Biomed Pharmacother . 2012 Jul; 66(5):323-9. PMID: 22770990
Thalidomide is used to treat a variety of diseases including erythema nodosum leprosum, an inflammatory complication of leprosy. However, this drug has severe teratogenic activity and novel thalidomide analogues might...
25.
Valle M, Saraiva M, Retailleau P, de Almeida M, Dodd R
J Org Chem . 2012 Jun; 77(13):5592-9. PMID: 22667756
4-Hydroxymethylbutenolide 4 was transformed into its sulfamoyl derivative 5, which upon treatment with iodosobenzene diacetate and magnesium oxide in the presence of a rhodium catalyst afforded the product of intramolecular...
26.
Silva A, Adade C, Shoyama F, Neto C, Padron T, de Almeida M, et al.
Biomed Pharmacother . 2012 Mar; 66(3):180-6. PMID: 22440898
Polyamine biosynthesis and inhibition in parasites have been an attractive chemotherapeutic approach in the design of novel antiparasitic drugs. We study in this work the effect of N-dodecyl-1,2-ethylenediamine (NDDE) on...
27.
de Faria T, Roman M, de Souza N, De Vecchi R, Vitor de Assis J, dos Santos A, et al.
Antimicrob Agents Chemother . 2012 Feb; 56(5):2259-67. PMID: 22330919
Nanoenabled drug delivery systems against tuberculosis (TB) are thought to control pathogen replication by targeting antibiotics to infected tissues and phagocytes. However, whether nanoparticle (NP)-based carriers directly interact with Mycobacterium...
28.
Giordani R, Junior C, de Andrade J, Bastida J, Zuanazzi J, Tasca T, et al.
Chem Biol Drug Des . 2012 Jan; 80(1):129-33. PMID: 22260620
Six lycorine derivatives were prepared, characterized, and evaluated for their in vitro anti-Trichomonas vaginalis activity. Compounds bearing an acetyl (2), lauroyl (3), benzoyl (4 and 5), and p-nitrobenzoyl (6 and...
29.
Correa C, Graudo J, De Oliveira L, de Almeida M, Diniz R
Acta Crystallogr Sect E Struct Rep Online . 2011 Nov; 67(Pt 8):o1967-8. PMID: 22091006
The title compound, C(6)H(11)N(3)O(2)S, consists of a roughly planar mol-ecule (r.m.s deviation from planarity = 0.077 Å for the non-H atoms) and has the S atom in an anti position...
30.
Correa C, Graudo J, De Oliveira L, de Almeida M, Diniz R
Acta Crystallogr Sect E Struct Rep Online . 2011 Nov; 67(Pt 8):o1882. PMID: 22090934
The title compound, C(6)H(11)N(3)O(3)·0.5H(2)O, has two independent mol-ecules and one mol-ecule of water in the asymmetric unit. The crystal packing is stabilized by inter-molecular N-H⋯N, O-H⋯O, N-H⋯O and C-H⋯O hydrogen...