Mauro V de Almeida
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Explore the profile of Mauro V de Almeida including associated specialties, affiliations and a list of published articles.
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45
Citations
207
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Recent Articles
11.
Chaves J, Tunes L, de J Franco C, Francisco T, Correa C, Murta S, et al.
Eur J Med Chem
. 2016 Nov;
127:727-739.
PMID: 27823888
The current anticancer and antileishmanial drug arsenal presents several limitations concerning their specificity, efficacy, costs and the emergence of drug-resistant cells lines, which encourages the urgent need to search for...
12.
de Souza Fernandes F, Fernandes T, da Silveira L, Caneschi W, Lourenco M, Diniz C, et al.
Eur J Med Chem
. 2015 Dec;
108:203-210.
PMID: 26649907
Three series of d-galactose derivatives linked to a lipophilic aminoalcohol moiety were synthesized and their antibacterial activity was evaluated against Mycobacterium tuberculosis and representative species of Gram positive and Gram...
13.
Yin H, de Almeida A, de Almeida M, Lindhardt A, Skrydstrup T
Org Lett
. 2015 Feb;
17(5):1248-51.
PMID: 25679260
A simple and mild method is demonstrated for assembling acyl carbamates through a base-free four-component Pd-catalyzed carbonylation of aryl halides in the presence of potassium cyanate and alcohols in a...
14.
de Almeida A, Andersen T, Lindhardt A, de Almeida M, Skrydstrup T
J Org Chem
. 2015 Jan;
80(3):1920-8.
PMID: 25565181
A useful method was developed for the synthesis of active esters by palladium-catalyzed alkoxycarbonylation of (hetero)aromatic bromides. The protocol was general for a range of oxygen nucleophiles including N-hydroxysuccinimide (NHS),...
15.
Junior C, Castro S, Pereira A, Alves C, Oliveira E, Rego R, et al.
Eur J Med Chem
. 2014 Aug;
85:615-20.
PMID: 25127153
The isoflavone genistein 1 and some derivatives modulate IL-12, TNF-α and NO production by macrophages and lung cancer cell lines, and improve the clinical signs of experimental autoimmune encephalomyelitis (EAE)....
16.
Mansur H, Mansur A, Curti E, de Almeida M
Carbohydr Polym
. 2014 Apr;
90(1):189-96.
PMID: 24751029
Novel carbohydrate-based hybrids combining chitosan and chemically modified chitosan with CdS inorganic nanoparticles were designed and prepared via aqueous route at room temperature. N,N,N-trimethylchitosan (TM-chitosan) was synthesized aiming at substantially...
17.
Teixeira M, de Assis J, Soares C, Venancio M, Lopes J, Nascimento Jr C, et al.
J Phys Chem B
. 2013 Dec;
118(1):81-93.
PMID: 24321011
Me-β-cyclodextrin (Me-βCD) and HP-β-cyclodextrin (HP-βCD) inclusion complexes with isoniazid (INH) were prepared with the aim of modulating the physicochemical and biopharmaceutical properties of the guest molecule, a well-known antibuberculosis drug....
18.
de Souza Fernandes F, Rezende Junior C, Fernandes T, da Silveira L, Rezende C, de Almeida M, et al.
Biomed Res Int
. 2013 Sep;
2013:783490.
PMID: 24024211
Polyamines are substances involved in many aspects of cell growth, division, and differentiation. Because of the metabolic differences between host cells and parasite cells, polyamine metabolism has been considered as...
19.
Yamanaka C, Giordani R, Rezende Jr C, Eger I, Kessler R, Tonini M, et al.
Chem Biol Drug Des
. 2013 Jul;
82(6):697-704.
PMID: 23865595
Leishmanicidal and trypanocidal activity of seventeen lipophilic diamines was evaluated in vitro against Leishmania braziliensis, L. chagasi, and Trypanosoma cruzi. Twelve compounds presented anti-Leishmania and six showed anti-T. cruzi amastigote...
20.
Correa T, Alves C, Castro S, Oliveira E, Franco L, Ferreira A, et al.
Chem Biol Drug Des
. 2013 Jul;
82(4):463-7.
PMID: 23819539
Mitoxantrone is an anthracenedione antineoplastic and immunosuppressive agent approved for multiple sclerosis treatment. Novel mono- and disubstituted anthraquinone derivatives, analogues of mitoxantrone, were synthesized through the addition of lipophilic amino...