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Mauro Delorenzi

Explore the profile of Mauro Delorenzi including associated specialties, affiliations and a list of published articles. Areas
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Articles 172
Citations 18538
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Recent Articles
1.
Martinez-Usatorre A, Ciarloni L, Angelino P, Wosika V, Conforte A, Fonseca Costa S, et al.
J Immunother Cancer . 2024 Nov; 12(11). PMID: 39577870
Background: Colorectal cancer (CRC) is the second leading cause of cancer-related deaths worldwide. CRC deaths can be reduced with prevention and early diagnosis. Circulating tumor DNA-based liquid biopsies, are emerging...
2.
Stalin J, Coquoz O, Jeitziner Marcone R, Jemelin S, Desboeufs N, Delorenzi M, et al.
Biomedicines . 2023 Dec; 11(12). PMID: 38137406
The melanoma cell adhesion molecule, shed from endothelial and cancer cells, is a soluble growth factor that induces tumor angiogenesis and growth. However, the molecular mechanism accounting for its generation...
3.
Banga R, Procopio F, Lana E, Gladkov G, Roseto I, Parsons E, et al.
Cell Host Microbe . 2023 Sep; 31(10):1714-1731.e9. PMID: 37751747
Although gut and lymph node (LN) memory CD4 T cells represent major HIV and simian immunodeficiency virus (SIV) tissue reservoirs, the study of the role of dendritic cells (DCs) in...
4.
Nguyen H, Geukens T, Maetens M, Aparicio S, Bassez A, Borg A, et al.
Nat Commun . 2023 Jul; 14(1):4418. PMID: 37479706
Obesity is associated with an increased risk of developing breast cancer (BC) and worse prognosis in BC patients, yet its impact on BC biology remains understudied in humans. This study...
5.
Romanens L, Chaskar P, Marcone R, Ryser S, Tille J, Genolet R, et al.
Int J Cancer . 2023 Jun; 153(9):1568-1578. PMID: 37306359
The spatial distribution of tumor-infiltrating lymphocytes (TIL) predicts breast cancer outcome and response to systemic therapy, highlighting the importance of an intact tissue structure for characterizing tumors. Here, we present...
6.
Gonzalez-Loyola A, Bernier-Latmani J, Roci I, Wyss T, Langer J, Durot S, et al.
J Exp Med . 2022 Sep; 219(12). PMID: 36121415
Small intestinal villi are structural and functional units present in higher vertebrates and uniquely adapted to nutrient absorption. Villus enterocytes are organized in transcriptional "zones" dedicated to specialized tasks such...
7.
Lorusso G, Wyss C, Kuonen F, Vannini N, Billottet C, Duffey N, et al.
Sci Transl Med . 2022 Sep; 14(661):eaax8933. PMID: 36070364
Brain metastasis is a complication of increasing incidence in patients with breast cancer at advanced disease stage. It is a severe condition characterized by a rapid decline in quality of...
8.
Bernier-Latmani J, Mauri C, Marcone R, Renevey F, Durot S, He L, et al.
Nat Commun . 2022 Jul; 13(1):3983. PMID: 35810168
The small intestinal villus tip is the first point of contact for lumen-derived substances including nutrients and microbial products. Electron microscopy studies from the early 1970s uncovered unusual spatial organization...
9.
Bernier-Latmani J, Cisarovsky C, Mahfoud S, Ragusa S, Dupanloup I, Barras D, et al.
Nat Cardiovasc Res . 2022 May; 1(5):476-490. PMID: 35602406
Stem and progenitor cells residing in the intestinal crypts drive the majority of colorectal cancers (CRCs), yet vascular contribution to this niche remains largely unexplored. VEGFA is a key driver...
10.
Fuertes Marraco S, Alpern D, Lofek S, Lourenco J, Bovay A, Maby-El Hajjami H, et al.
Curr Res Immunol . 2022 May; 3:1-12. PMID: 35496820
CD8 T cells have multiple functional properties that mediate acute phase and long-term immune protection. Several effector and memory CD8 T cell subsets have been described with diverse functionalities and...