Christos Sotiriou
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Explore the profile of Christos Sotiriou including associated specialties, affiliations and a list of published articles.
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287
Citations
25561
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Recent Articles
1.
Metoikidou C, Karnaukhov V, Boeckx B, Timperi E, Bonte P, Wang L, et al.
Cell Rep Med
. 2025 Feb;
:101973.
PMID: 39983715
Chemotherapy combined with immune checkpoint blockade has shown clinical activity in breast cancer. Response, however, occurs in only a low proportion of patients. How the immune landscape of the tumor...
2.
Kouvaraki M, Zerdes I, Sifakis E, Sarafidis M, Matikas A, Tzoras E, et al.
Int J Cancer
. 2024 Dec;
156(8):1621-1633.
PMID: 39729390
Sterile alpha motif and HD domain-containing protein 1 (SAMHD1) is a dNTP hydrolase important for intracellular dNTP homeostasis and serves as tumor suppressor and modulator of antimetabolite efficacy in cancer,...
3.
Fernandez-Martinez A, Fernandez-Martinez A, Tanioka M, Tanioka M, Ahn S, Ahn S, et al.
Ann Oncol
. 2024 Dec;
PMID: 39706338
Background: In human epidermal growth factor receptor 2 (HER2)-positive early breast cancer (EBC), we investigated tumor and immune changes during neoadjuvant treatment and their impact on residual disease (RD) biology...
4.
Laurent P, Andre F, Bobard A, Deandreis D, Demaria S, Depil S, et al.
Oncoimmunology
. 2024 Dec;
14(1):2432726.
PMID: 39696783
Over the last decade, the annual Immunorad Conference, held under the joint auspicies of Gustave Roussy (Villejuif, France) and the Weill Cornell Medical College (New-York, USA) has aimed at exploring...
5.
Rediti M, Venet D, Joaquin Garcia A, Maetens M, Vincent D, Majjaj S, et al.
Nat Commun
. 2024 Nov;
15(1):10402.
PMID: 39613746
In HER2-positive breast cancer, clinical outcome and sensitivity to HER2-targeted therapies are influenced by both tumor and microenvironment features. However, we are currently unable to depict the molecular heterogeneity of...
6.
Wang X, Venet D, Lifrange F, Larsimont D, Rediti M, Stenbeck L, et al.
Nat Commun
. 2024 Nov;
15(1):10232.
PMID: 39592577
While triple-negative breast cancer (TNBC) is known to be heterogeneous at the genomic and transcriptomic levels, spatial information on tumor organization and cell composition is still lacking. Here, we investigate...
7.
Rediti M, Fimereli D, Mileva M, Wimana Z, Venet D, Flamen P, et al.
Clin Cancer Res
. 2024 Oct;
31(1):110-121.
PMID: 39470686
Purpose: The ZEPHIR clinical trial evaluated the role of [89Zr]trastuzumab-PET/CT (HER2-PET/CT) and 2-[18F]fluoro-2-deoxy-D-glucose PET/CT ([18F]FDG-PET/CT) in predicting outcomes in patients with advanced HER2-positive breast cancer treated with trastuzumab emtansine (T-DM1)....
8.
Oesterreich S, Pate L, Lee A, Chen F, Jankowitz R, Mukhtar R, et al.
NPJ Breast Cancer
. 2024 Jul;
10(1):61.
PMID: 39033157
There is growing awareness of the unique etiology, biology, and clinical presentation of invasive lobular breast cancer (ILC), but additional research is needed to ensure translation of findings into management...
9.
Fernandez-Martinez A, Rediti M, Tang G, Pascual T, Hoadley K, Venet D, et al.
JAMA Oncol
. 2024 Mar;
10(5):603-611.
PMID: 38546612
Importance: Biologic features may affect pathologic complete response (pCR) and event-free survival (EFS) after neoadjuvant chemotherapy plus ERBB2/HER2 blockade in ERBB2/HER2-positive early breast cancer (EBC). Objective: To define the quantitative...
10.
Jahangir C, Page D, Broeckx G, Gonzalez C, Burke C, Murphy C, et al.
J Pathol
. 2024 Jan;
262(3):271-288.
PMID: 38230434
Recent advances in the field of immuno-oncology have brought transformative changes in the management of cancer patients. The immune profile of tumours has been found to have key value in...