Matthew J Murtha
Overview
Explore the profile of Matthew J Murtha including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
730
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Recent Articles
1.
Bender K, Schwartz L, Cohen A, Mosquera Vasquez C, Murtha M, Eichler T, et al.
Am J Physiol Renal Physiol
. 2021 Apr;
320(5):F972-F983.
PMID: 33818125
Antimicrobial peptides are essential host defense mechanisms that prevent urinary tract infections. Recent studies have demonstrated that peptides in the ribonuclease A superfamily have antimicrobial activity against uropathogens and protect...
2.
Eichler T, Bender K, Murtha M, Schwartz L, Metheny J, Solden L, et al.
J Am Soc Nephrol
. 2019 Jun;
30(8):1385-1397.
PMID: 31239387
Background: Evidence suggests that antimicrobial peptides, components of the innate immune response, protect the kidneys and bladder from bacterial challenge. We previously identified ribonuclease 7 (RNase 7) as a human...
3.
Murtha M, Eichler T, Bender K, Metheny J, Li B, Schwaderer A, et al.
J Clin Invest
. 2018 Nov;
128(12):5634-5646.
PMID: 30418175
People with diabetes mellitus have increased infection risk. With diabetes, urinary tract infection (UTI) is more common and has worse outcomes. Here, we investigate how diabetes and insulin resistance impact...
4.
Garg S, Lioy D, Cheval H, McGann J, Bissonnette J, Murtha M, et al.
J Neurosci
. 2013 Aug;
33(34):13612-20.
PMID: 23966684
De novo mutations in the X-linked gene encoding the transcription factor methyl-CpG binding protein 2 (MECP2) are the most frequent cause of the neurological disorder Rett syndrome (RTT). Hemizygous males...
5.
Haidet-Phillips A, Hester M, Miranda C, Meyer K, Braun L, Frakes A, et al.
Nat Biotechnol
. 2011 Aug;
29(9):824-8.
PMID: 21832997
Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease, with astrocytes implicated as contributing substantially to motor neuron death in familial (F)ALS. However, the proposed role of astrocytes in...
6.
Hester M, Murtha M, Song S, Rao M, Miranda C, Meyer K, et al.
Mol Ther
. 2011 Jul;
19(10):1905-12.
PMID: 21772256
Stem cell-derived motor neurons (MNs) are increasingly utilized for modeling disease in vitro and for developing cellular replacement strategies for spinal cord injury and diseases such as spinal muscular atrophy...