Brian Becknell
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Explore the profile of Brian Becknell including associated specialties, affiliations and a list of published articles.
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108
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3017
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Recent Articles
1.
van der Plas E, Nelson E, Becknell B, Dawson A, Wilson C, Dawson J, et al.
JAMA Netw Open
. 2025 Feb;
8(2):e2457601.
PMID: 39899296
Importance: Pediatric patients with chronic kidney disease (CKD) exhibit reduced cerebellum volume, which is associated with neurocognitive deficits and a lower estimated glomerular filtration rate (eGFR), even before dialysis or...
2.
Cotzomi-Ortega I, Rosowski E, Wang X, Sanchez-Zamora Y, Lopez-Torres J, Sanchez-Orellana G, et al.
Mucosal Immunol
. 2024 Dec;
PMID: 39710133
The precise role of neutrophil-derived reactive oxygen species (ROS) in combating bacterial uropathogens during urinary tract infections (UTI) remains largely unexplored. In this study, we elucidate the antimicrobial significance of...
3.
Jackson A, El-Harakeh M, Rodriguez-Tirado F, Miehls A, Hardman A, Camara O, et al.
Res Sq
. 2024 Dec;
PMID: 39678328
Urinary tract obstruction (UTO) is a common cause of kidney injury that can result in chronic kidney disease and end-stage renal disease. Heterogeneity in the extent of obstructive renal damage...
4.
Jackson A, Amado N, Mann N, Schanstra J, Ruano R, Mohamed T, et al.
Nat Rev Urol
. 2024 Nov;
PMID: 39613986
No abstract available.
5.
6.
Salamon K, Linn-Peirano S, Simoni A, Ruiz-Rosado J, Becknell B, John P, et al.
Diabetes Obes Metab
. 2024 Sep;
27(1):40-53.
PMID: 39344841
Aim: Sodium-glucose co-transporter-2 (SGLT2) inhibitors have revolutionized clinical medicine, but their association with urinary tract infection (UTI) risk remains debated. This study investigates the influence of dapagliflozin on UTI outcomes,...
7.
Cortado H, Kercsmar M, Li B, Vasquez-Martinez G, Gupta S, Ching C, et al.
J Innate Immun
. 2024 May;
16(1):283-294.
PMID: 38744252
Introduction: The ribonuclease (RNase) A superfamily encodes cationic antimicrobial proteins with potent microbicidal activity toward uropathogenic bacteria. Ribonuclease 6 (RNase6) is an evolutionarily conserved, leukocyte-derived antimicrobial peptide with potent microbicidal...
8.
Becknell B, El-Harakeh M, Rodriguez-Tirado F, Grounds K, Li B, Kercsmar M, et al.
Am J Physiol Renal Physiol
. 2024 Apr;
326(6):F1078-F1090.
PMID: 38634130
Urothelium forms a distensible yet impermeable barrier, senses and transduces stimuli, and defends the urinary tract from mechanical, chemical, and bacterial injuries. Biochemical and genetic labeling studies support the existence...
9.
Schwartz L, Salamon K, Simoni A, Eichler T, Jackson A, Murtha M, et al.
Cell Rep
. 2024 Mar;
43(4):114007.
PMID: 38517889
Urinary tract infections (UTIs) commonly afflict people with diabetes. To better understand the mechanisms that predispose diabetics to UTIs, we employ diabetic mouse models and altered insulin signaling to show...
10.
Jebbia M, Gupta S, Klamer B, Pavlek L, Ching C, Mohamed T, et al.
Sci Rep
. 2024 Feb;
14(1):2996.
PMID: 38316971
Urinary tract infections (UTIs) are a common comorbidity in hospitalized neonates. The current UTI diagnostics have several limitations including invasive collection of urinary samples to ensure sterility, risk of contamination...