Masaaki Okamoto
Overview
Explore the profile of Masaaki Okamoto including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
42
Citations
531
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Nakayama Y, Sasai M, Kuratani A, Okamoto M, Okuzaki D, Yamamoto K, et al.
iScience
. 2025 Mar;
28(3):111975.
PMID: 40060898
Alveolar macrophages (AMs) are essential for maintaining lung homeostasis. However, their roles in respiratory infections have been controversial because the methods of depleting them have often suffered from poor cell...
2.
Kuratani A, Okamoto M, Kishida K, Okuzaki D, Sasai M, Sakaguchi S, et al.
Science
. 2024 Nov;
386(6724):eadn8608.
PMID: 39571033
The tumor microenvironment (TME) contains a number of immune-suppressive cells such as T helper 1-polarized regulatory T cells (T1-T cells). However, little is known about the mechanism behind the abundant...
3.
Okamoto M, Kuratani A, Okuzaki D, Kamiyama N, Kobayashi T, Sasai M, et al.
Proc Natl Acad Sci U S A
. 2024 Nov;
121(48):e2401692121.
PMID: 39560646
Experimental autoimmune encephalomyelitis (EAE) is the most widely used rodent model for multiple sclerosis. Interferon-γ (IFN-γ) and regulatory T cells (Tregs) are individually well known to play beneficial roles in...
4.
Okamoto M, Kuratani A, Okuzaki D, Kamiyama N, Kobayashi T, Sasai M, et al.
Front Immunol
. 2024 Sep;
15:1440918.
PMID: 39286257
Bleomycin (BLM) induces lung injury, leading to inflammation and pulmonary fibrosis. Regulatory T cells (Tregs) maintain self-tolerance and control host immune responses. However, little is known about their involvement in...
5.
Kamiyama N, Ueno M, Sasaki Y, Chalalai T, Sachi N, Ozaka S, et al.
Int Immunol
. 2024 Jul;
37(1):39-52.
PMID: 39051675
Toxoplasma gondii (T. gondii) is a zoonotic protozoan parasite that causes congenital toxoplasmosis, including fetal death, abortion, stillbirth, morphological abnormalities, and premature birth. Primary T. gondii infection in pregnant women...
6.
Okamoto M, Yamamoto M
Adv Exp Med Biol
. 2024 Mar;
1444:177-193.
PMID: 38467980
T cells play a crucial role in adaptive immunity by recognizing and eliminating foreign pathogens and abnormal cells such as cancer cells. T cell receptor (TCR), which is expressed on...
7.
Wint W, Miyanohara M, Yamada H, Nakatsuka T, Okamoto M, Ryo K, et al.
Diagn Microbiol Infect Dis
. 2024 Feb;
109(1):116214.
PMID: 38402755
Colonization by several oral pathogens and the onset of oral diseases, such as dental caries and periodontal diseases, are closely related. Therefore, the analysis of pathogens in oral specimens would...
8.
Okamoto M, Sasai M, Kuratani A, Okuzaki D, Arai M, Wing J, et al.
Cell Rep
. 2023 Jul;
42(7):112813.
PMID: 37440410
Regulatory T (Treg) cells expressing the transcription factor (TF) Foxp3 also express other TFs shared by T helper (Th) subsets under certain conditions. Here, to determine the roles of T-bet-expressing...
9.
Miyashita Y, Kouwaki T, Tsukamoto H, Okamoto M, Nakamura K, Oshiumi H
Life Sci Alliance
. 2021 Nov;
5(2).
PMID: 34819358
TICAM-1 (also called TRIF) is the sole adaptor of TLR3 that recognizes double-stranded RNA. Here, we report that TICAM-1 is involved not only in TLR3 signaling but also in the...
10.
Uncovering a novel role of PLCβ4 in selectively mediating TCR signaling in CD8+ but not CD4+ T cells
Sasai M, Ma J, Okamoto M, Nishino K, Nagaoka H, Takashima E, et al.
J Exp Med
. 2021 May;
218(7).
PMID: 33970189
Because of their common signaling molecules, the main T cell receptor (TCR) signaling cascades in CD4+ and CD8+ T cells are considered qualitatively identical. Herein, we show that TCR signaling...