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Martha Campbell-Thompson

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Articles 128
Citations 4344
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Recent Articles
1.
Cheng T, Fu D, Falzarano S, Zhang R, Datta S, Zhang W, et al.
Int J Mol Sci . 2025 Jan; 25(24. PMID: 39769193
This hypothesis-generating study aims to examine the extent to which computed tomography-assessed body composition phenotypes are associated with immune and phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT) signaling pathways in breast...
2.
Huber M, Widener A, Cuaycal A, Smurlick D, Butterworth E, Lenchik N, et al.
bioRxiv . 2025 Jan; PMID: 39763971
The loss of insulin secretory function associated with type 1 diabetes (T1D) is attributed to the immune-mediated destruction of beta cells. Yet, at onset of T1D, patients often have a...
3.
Kang S, Penaloza Aponte J, Elashkar O, Morales J, Waddington N, Lamb D, et al.
J Pathol Inform . 2024 Dec; 16:100406. PMID: 39720415
Human islets display a high degree of heterogeneity in terms of size, number, architecture, and endocrine cell-type compositions. An ever-increasing number of immunohistochemistry-stained whole slide images (WSIs) are available through...
4.
Bruggeman B, Gornisiewicz S, Bacher R, McGrail K, Campbell-Thompson M, Wasserfall C, et al.
Front Endocrinol (Lausanne) . 2024 Dec; 15:1497373. PMID: 39678192
Introduction: The immune-mediated destruction of insulin-producing β-cells characterizes type 1 diabetes. Nevertheless, exocrine pancreatic enzymes, including amylase, lipase, and trypsin, are also significantly reduced in type 1 diabetes. With an...
5.
Swensen A, Piehowski P, Chen J, Chan X, Kelly S, Petyuk V, et al.
bioRxiv . 2024 Sep; PMID: 39345556
Aims/hypothesis: Progression to type 1 diabetes (T1D) is associated with genetic factors, the presence of autoantibodies, and a decline in β cell insulin secretion in response to glucose. Very little...
6.
Kwon Y, Woo J, Yu F, Williams S, Markillie L, Moore R, et al.
Mol Cell Proteomics . 2024 Sep; 23(11):100841. PMID: 39307423
Multiplexed bimolecular profiling of tissue microenvironment, or spatial omics, can provide deep insight into cellular compositions and interactions in healthy and diseased tissues. Proteome-scale tissue mapping, which aims to unbiasedly...
7.
Spilseth B, Fogel E, Toledo F, Campbell-Thompson M
Curr Opin Gastroenterol . 2024 Jul; 40(5):381-388. PMID: 38967933
Purpose Of Review: Radiographic imaging of the pancreas has drawn recent interest as pancreas volume may serve as a biomarker in identifying the likelihood of diabetes development, subtyping diabetes, and...
8.
Morales J, Klose M, Hoffert Y, Podichetty J, Burton J, Schmidt S, et al.
CPT Pharmacometrics Syst Pharmacol . 2024 Jul; 13(8):1309-1316. PMID: 38961520
Clinical trials seeking to delay or prevent the onset of type 1 diabetes (T1D) face a series of pragmatic challenges. Despite more than 100 years since the discovery of insulin,...
9.
Cheng T, Fu D, Falzarano S, Zhang R, Datta S, Zhang W, et al.
medRxiv . 2024 Jun; PMID: 38826360
This hypothesis-generating study aims to examine the extent to which computed tomography-assessed body composition phenotypes are associated with immune and PI3K/AKT signaling pathways in breast tumors. A total of 52...
10.
Kwon Y, Woo J, Yu F, Williams S, Markillie L, Moore R, et al.
bioRxiv . 2024 Mar; PMID: 38496682
Multiplexed bimolecular profiling of tissue microenvironment, or spatial omics, can provide deep insight into cellular compositions and interactions in healthy and diseased tissues. Proteome-scale tissue mapping, which aims to unbiasedly...