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Alberto Pugliese

Explore the profile of Alberto Pugliese including associated specialties, affiliations and a list of published articles. Areas
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Articles 121
Citations 3543
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Recent Articles
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Diedisheim M, Mallone R, Pugliese A, Dubois-Laforgue D, Larger E
J Clin Endocrinol Metab . 2025 Jan; PMID: 39873482
Context: Type 1 diabetes (T1D) is characterized by the presence of autoantibodies on a genetic background largely determined by HLA class II haplotypes. Stage 1 T1D is characterized by the...
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Mallone R, Sims E, Achenbach P, Mathieu C, Pugliese A, Atkinson M, et al.
Diabetes . 2024 Oct; 74(1):12-21. PMID: 39446565
Article Highlights:
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Zhao L, Papadopoulos G, Skyler J, Pugliese A, Parikh H, Kwok W, et al.
Diabetologia . 2024 Oct; 67(11):2481-2493. PMID: 39354095
Aims/hypothesis: The aim of this work was to explore molecular amino acids (AAs) and related structures of HLA-DQA1-DQB1 that underlie its contribution to the progression from stages 1 or 2...
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Laiho J, Oikarinen S, Morfopoulou S, Oikarinen M, Renner A, Depledge D, et al.
medRxiv . 2024 Sep; PMID: 39314969
Aims/hypothesis: The nPOD-Virus group collaboratively applied innovative technologies to detect and sequence viral RNA in pancreas and other tissues from organ donors with type 1 diabetes. These analyses involved the...
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Kusmartseva I, Posgai A, Yang M, Oram R, Atkinson M, Pugliese A, et al.
Cold Spring Harb Perspect Med . 2024 Aug; PMID: 39134385
The Network for Pancreatic Organ Donors with Diabetes (nPOD) has helped shape the contemporary understanding of type 1 diabetes (T1D) pathogenesis in humans through the procurement, distribution to scientists, and...
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Linsley P, Nakayama M, Balmas E, Chen J, Barahmand-Pour-Whitman F, Bansal S, et al.
Nat Commun . 2024 Jun; 15(1):4971. PMID: 38871688
Human type 1 diabetes (T1D) is caused by autoimmune attack on the insulin-producing pancreatic beta cells by islet antigen-reactive T cells. How human islet antigen-reactive (IAR) CD4+ memory T cells...
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Sebastiani G, Grieco G, Bruttini M, Auddino S, Mori A, Toniolli M, et al.
Cell Rep Med . 2024 Jun; 5(6):101591. PMID: 38838677
Circulating microRNAs (miRNAs) are linked to the onset and progression of type 1 diabetes mellitus (T1DM), thus representing potential disease biomarkers. In this study, we employed a multiplatform sequencing approach...
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Jacobsen L, Cuthbertson D, Bundy B, Atkinson M, Moore W, Haller M, et al.
Diabetes Care . 2024 Apr; 47(6):1048-1055. PMID: 38621411
Objective: Mixed-meal tolerance test-stimulated area under the curve (AUC) C-peptide at 12-24 months represents the primary end point for nearly all intervention trials seeking to preserve β-cell function in recent-onset...
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Panzer J, Garcia P, Pugliese A
J Vis Exp . 2024 Apr; (205). PMID: 38557588
It is crucial to study the human pancreas to understand the pathophysiological mechanisms associated with type 1 (T1D) and 2 diabetes (T2D) as well as the pancreas endocrine and exocrine...