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Mark Atkinson

Explore the profile of Mark Atkinson including associated specialties, affiliations and a list of published articles. Areas
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Articles 135
Citations 4177
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Recent Articles
1.
Melton R, Jimenez S, Elison W, Tucciarone L, Howell A, Wang G, et al.
bioRxiv . 2025 Mar; PMID: 40027657
Cell type-specific regulatory programs that drive type 1 diabetes (T1D) in the pancreas are poorly understood. Here we performed single nucleus multiomics and spatial transcriptomics in up to 32 non-diabetic...
2.
Calhoun P, Spanbauer C, Steck A, Frohnert B, Herman M, Keymeulen B, et al.
Diabetologia . 2025 Feb; PMID: 39934369
Aims/hypothesis: We aimed to assess whether continuous glucose monitor (CGM) metrics can accurately predict stage 3 type 1 diabetes diagnosis in those with islet autoantibodies (AAb). Methods: Baseline CGM data...
3.
Williams M, Grace C, Posgai A, McGrail K, Brusko M, Haller M, et al.
BMJ Open Diabetes Res Care . 2025 Jan; 13(1. PMID: 39755561
Introduction: Altered serum levels of growth hormones, adipokines, and exocrine pancreas enzymes have been individually linked with type 1 diabetes (T1D). We collectively evaluated seven such biomarkers, combined with islet...
4.
Bruggeman B, Gornisiewicz S, Bacher R, McGrail K, Campbell-Thompson M, Wasserfall C, et al.
Front Endocrinol (Lausanne) . 2024 Dec; 15:1497373. PMID: 39678192
Introduction: The immune-mediated destruction of insulin-producing β-cells characterizes type 1 diabetes. Nevertheless, exocrine pancreatic enzymes, including amylase, lipase, and trypsin, are also significantly reduced in type 1 diabetes. With an...
5.
Redondo M, Cuthbertson D, Steck A, Herold K, Oram R, Atkinson M, et al.
Diabetologia . 2024 Dec; 68(3):588-601. PMID: 39670998
Aims/hypothesis: Many studies of type 1 diabetes pathogenesis focus on individuals with high-risk HLA haplotypes. We tested the hypothesis that, among islet autoantibody-positive individuals, lacking HLA-DRB1*04-DQA1*03-DQB1*0302 (HLA-DR4-DQ8) and/or HLA-DRB1*0301-DQA1*0501-DQB1*0201 (HLA-DR3-DQ2)...
6.
Mallone R, Sims E, Achenbach P, Mathieu C, Pugliese A, Atkinson M, et al.
Diabetes . 2024 Oct; 74(1):12-21. PMID: 39446565
Article Highlights:
7.
Kusmartseva I, Posgai A, Yang M, Oram R, Atkinson M, Pugliese A, et al.
Cold Spring Harb Perspect Med . 2024 Aug; PMID: 39134385
The Network for Pancreatic Organ Donors with Diabetes (nPOD) has helped shape the contemporary understanding of type 1 diabetes (T1D) pathogenesis in humans through the procurement, distribution to scientists, and...
8.
Gray J, Caron D, Wells S, Guyer R, Szabo P, Rainbow D, et al.
Sci Immunol . 2024 Jun; 9(96):eadn3954. PMID: 38848342
During ontogeny, γδ T cells emerge from the thymus and directly seed peripheral tissues for in situ immunity. However, their functional role in humans has largely been defined from blood....
9.
Langelier C, Pickering H, Schaenman J, Phan H, Maguire C, Tsitsiklis A, et al.
Res Sq . 2024 Jan; PMID: 38196658
Coronavirus disease 2019 (COVID-19) poses significant risks for solid organ transplant (SOT) recipients, who have atypical but poorly characterized immune responses to SARS-CoV-2 infection. We sought to understand and the...
10.
Beran D, Koch M, Ajmal S, de Beaufort C, Ramaiya K, Zafra-Tanaka J, et al.
Lancet Diabetes Endocrinol . 2023 Nov; 12(1):9-11. PMID: 37972630
No abstract available.