Mark V Boekschoten
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Explore the profile of Mark V Boekschoten including associated specialties, affiliations and a list of published articles.
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88
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3309
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Recent Articles
1.
Mohamed M, Haybaeck J, Wu H, Su H, Bartneck M, Lin C, et al.
JHEP Rep
. 2023 Oct;
5(11):100854.
PMID: 37791376
Background & Aims: Cholestatic liver injury is associated with c-Jun N-terminal kinases (JNK) activation in distinct cell types. Its hepatocyte-specific function during cholestasis, however, has not yet been established. Therefore,...
2.
Vucur M, Ghallab A, Schneider A, Adili A, Cheng M, Castoldi M, et al.
Immunity
. 2023 Jun;
56(7):1578-1595.e8.
PMID: 37329888
It is currently not well known how necroptosis and necroptosis responses manifest in vivo. Here, we uncovered a molecular switch facilitating reprogramming between two alternative modes of necroptosis signaling in...
3.
Kuwabara R, Qin T, Alberto Llacua L, Hu S, Boekschoten M, de Haan B, et al.
Acta Biomater
. 2023 Jan;
158:151-162.
PMID: 36610609
Immunoisolation of pancreatic-islets in alginate-microcapsules is applied to treat diabetes. However, long-term islet function is limited, which might be due to damaged and lack of contact with pancreatic extracellular matrix...
4.
de Bus I, van Krimpen S, Hooiveld G, Boekschoten M, Poland M, Witkamp R, et al.
Biochim Biophys Acta Mol Cell Biol Lipids
. 2021 Feb;
1866(6):158908.
PMID: 33610761
Docosahexaenoyl ethanolamide (DHEA), the ethanolamine conjugate of the n-3 long chain polyunsaturated fatty acid docosahexaenoic acid, is endogenously present in the human circulation and in tissues. Its immunomodulating properties have...
5.
Cubero F, Mohamed M, Woitok M, Zhao G, Hatting M, Nevzorova Y, et al.
Hepatol Commun
. 2020 Jun;
4(6):834-851.
PMID: 32490320
Targeted inhibition of the c-Jun N-terminal kinases (JNKs) has shown therapeutic potential in intrahepatic cholangiocarcinoma (CCA)-related tumorigenesis. However, the cell-type-specific role and mechanisms triggered by JNK in liver parenchymal cells...
6.
Lip S, Boekschoten M, Hooiveld G, van Pampus M, Scherjon S, Plosch T, et al.
Am J Obstet Gynecol
. 2019 Dec;
222(5):497.e1-497.e12.
PMID: 31836544
Background: Preeclampsia is a hypertensive pregnancy disorder in which generalized systemic inflammation and maternal endothelial dysfunction are involved in the pathophysiology. MiRNAs are small noncoding RNAs responsible for post-transcriptional regulation...
7.
Vinke P, Bowen T, Boekschoten M, Witkamp R, Adams V, van Norren K
Sci Rep
. 2019 Jul;
9(1):10160.
PMID: 31308383
Pulmonary arterial hypertension (PAH) is characterized by remodelling of the pulmonary arteries and right ventricle (RV), which leads to functional decline of cardiac and skeletal muscle. This study investigated the...
8.
Hangelbroek R, Vaes A, Boekschoten M, Verdijk L, Hooiveld G, van Loon L, et al.
BMC Geriatr
. 2019 May;
19(1):151.
PMID: 31138136
Objective: Vitamin D deficiency is common among older adults and has been linked to muscle weakness. Vitamin D supplementation has been proposed as a strategy to improve muscle function in...
9.
Sovran B, Hugenholtz F, Elderman M, van Beek A, Graversen K, Huijskes M, et al.
Sci Rep
. 2019 Feb;
9(1):1437.
PMID: 30723224
Aging significantly increases the vulnerability to gastrointestinal (GI) disorders but there are few studies investigating the key factors in aging that affect the GI tract. To address this knowledge gap,...
10.
Sergi D, Campbell F, Grant C, Morris A, Bachmair E, Koch C, et al.
Genes Nutr
. 2018 Dec;
13:28.
PMID: 30519364
Background: Energy homeostasis is regulated by the hypothalamus but fails when animals are fed a high-fat diet (HFD), and leptin insensitivity and obesity develops. To elucidate the possible mechanisms underlying...