Sander Kersten
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Explore the profile of Sander Kersten including associated specialties, affiliations and a list of published articles.
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209
Citations
10668
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Recent Articles
1.
Attema B, de la Rosa Rodriguez M, van Schothorst E, Grefte S, Hooiveld G, Kersten S
Mol Metab
. 2025 Jan;
92:102092.
PMID: 39746607
Objective: The peroxisome proliferator-activated receptor-alpha (PPARα) plays a central role in lipid metabolism in the liver by stimulating the expression of hundreds of genes. Accordingly, regulation by PPARα could be...
2.
Attema B, Kummu O, Krutakova M, Pavek P, Hakkola J, Hooiveld G, et al.
Arch Toxicol
. 2024 Dec;
99(3):1203-1221.
PMID: 39718591
Propiconazole is a triazole fungicide previously shown to induce triglyceride accumulation in human liver HepaRG cells, potentially via activation of the Pregnane X Receptor (PXR). However, whether propiconazole can disrupt...
3.
Sellers A, van Beek S, Hashim D, Baak R, Pallubinsky H, Moonen-Kornips E, et al.
Nat Metab
. 2024 Dec;
6(12):2246-2253.
PMID: 39643644
Cold acclimation increases insulin sensitivity, and some level of muscle contraction appears to be needed for provoking this effect. Here 15 men and (postmenopausal) women with overweight or obesity, the...
4.
Vrieling F, van der Zande H, Naus B, Smeehuijzen L, van Heck J, Ignacio B, et al.
Cell Rep Methods
. 2024 Oct;
4(10):100883.
PMID: 39437716
Cellular energy metabolism significantly contributes to immune cell function. To further advance immunometabolic research, novel methods to study the metabolism of immune cells in complex samples are required. Here, we...
5.
Landfors F, Henneman P, Chorell E, Nilsson S, Kersten S
Eur Heart J Open
. 2024 Jun;
4(3):oeae035.
PMID: 38895109
Aims: APOC3, ANGPTL3, and ANGPTL4 are circulating proteins that are actively pursued as pharmacological targets to treat dyslipidaemia and reduce the risk of atherosclerotic cardiovascular disease. Here, we used human...
6.
Deng M, Kersten S
J Lipid Res
. 2024 Mar;
65(4):100526.
PMID: 38431115
ANGPTL4 is an attractive pharmacological target for lowering plasma triglycerides and cardiovascular risk. Since most preclinical studies on ANGPTL4 were performed in male mice, little is known about sexual dimorphism...
7.
Attema B, Kummu O, Pitkanen S, Weisell J, Vuorio T, Pennanen E, et al.
Arch Toxicol
. 2024 Jan;
98(3):911-928.
PMID: 38182912
Environmental exposure to endocrine-disrupting chemicals (EDCs) can lead to metabolic disruption, resulting in metabolic complications including adiposity, dyslipidemia, hepatic lipid accumulation, and glucose intolerance. Hepatic nuclear receptor activation is one...
8.
Daanje M, Siebelink E, Vrieling F, van den Belt M, van der Haar S, Gerdessen J, et al.
Front Nutr
. 2023 Dec;
10:1281978.
PMID: 38152465
Introduction: An elevated postprandial glucose response is associated with an increased risk of cardiometabolic diseases. Existing research suggests large heterogeneity in the postprandial glucose responses to identical meals and food...
9.
Deng L, Michielsen C, Vrieling F, Hooiveld G, Stienstra R, Feitsma A, et al.
Clin Nutr
. 2023 Dec;
43(1):232-245.
PMID: 38101314
Background: Intake of high-fat foods raises postprandial plasma triglycerides and inflammatory markers, which may depend on the type of fat ingested. Dairy products are commonly consumed, but not much is...
10.
Ruppert P, Kersten S
Trends Endocrinol Metab
. 2023 Nov;
35(2):107-124.
PMID: 37940485
Fasting is part of many weight management and health-boosting regimens. Fasting causes substantial metabolic adaptations in the liver that include the stimulation of fatty acid oxidation and ketogenesis. The induction...