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Paul de Vos

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Articles 448
Citations 10152
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Recent Articles
1.
Moeun B, Lemaire F, Smink A, Ebrahimi Orimi H, Leask R, de Vos P, et al.
J Tissue Eng . 2025 Jan; 16:20417314241284826. PMID: 39866963
Islet transplantation and more recently stem cell-derived islets were shown to successfully re-establish glycemic control in people with type 1 diabetes under immunosuppression. These results were achieved through intraportal infusion...
2.
Pedrosa L, de Vos P, Fabi J
Nutrients . 2025 Jan; 16(24. PMID: 39770907
The microbiota stability, diversity, and composition are pillars for an efficient and beneficial symbiotic relationship between its host and itself. Microbial dysbiosis, a condition where a homeostatic bacterial community is...
3.
Silva-Lagos L, Ijaz A, Buwalda P, Kassai S, Klostermann C, Leemhuis H, et al.
Carbohydr Polym . 2024 Dec; 350:122980. PMID: 39647934
Isomalto/malto-polysaccharides (IMMPs) are α-glucans with prebiotic potential used as food ingredients. However, their ability to exert direct cellular effects remains unknown. IMMPs may enhance immunity by activating toll-like receptors (TLRs),...
4.
Akkerman R, Oerlemans M, Ferrari M, Fernandez-Lainez C, Walvoort M, de Vos P
Carbohydr Polym . 2024 Dec; 349(Pt B):123017. PMID: 39638524
Background: Exopolysaccharides (EPS) from probiotic bacteria like bifidobacteria, have gained considerable attention for the beneficial effects they exert in the gastrointestinal environment. Here, we investigated whether EPS isolated from Bifidobacterium...
5.
Tuohy K, Vaughan E, Harthoorn L, Blaak E, Burnet P, Busetti A, et al.
Gut Microbes . 2024 Nov; 16(1):2428848. PMID: 39544074
Numerous studies have established that prebiotic ingredients in foods and dietary supplements may play a role in supporting human health. Over the three decades that have passed since prebiotics were...
6.
Ferrari M, van Leeuwen S, de Vos P, Jurak E, Walvoort M
Carbohydr Polym . 2024 Nov; 347:122660. PMID: 39486922
Bifidobacteria, which are increasingly linked to health benefits to the host, produce structurally complex exopolysaccharides which are considered to be effector molecules responsible for health effects. It is currently not...
7.
Chen X, Gasaly N, Tang X, Walvoort M, de Vos P
Curr Res Food Sci . 2024 Sep; 9:100851. PMID: 39314222
The intestinal epithelium is an important gatekeeper of the human body by forming a barrier for the luminal content of the intestine. The barrier function is regulated by a complex...
8.
Grattoni A, Korbutt G, Tomei A, Garcia A, Pepper A, Stabler C, et al.
Nat Rev Endocrinol . 2024 Sep; 21(1):14-30. PMID: 39227741
Type 1 diabetes mellitus (T1DM) is a growing global health concern that affects approximately 8.5 million individuals worldwide. T1DM is characterized by an autoimmune destruction of pancreatic β cells, leading...
9.
Qin T, Hu S, Kong D, Lakey J, de Vos P
Mater Today Bio . 2024 Jul; 27:101129. PMID: 39022526
Pancreatic islet transplantation is proposed as a cure for type 1 diabetes mellitus (T1D). Despite its success in optimal regulation of glucose levels, limitations in longevity of islet grafts still...
10.
Boven L, Akkerman R, de Vos P
Crit Rev Food Sci Nutr . 2024 Jul; :1-11. PMID: 38950600
The human diet requires a more plant-based approach due to the exhaustive effects animal-based foods have on the environment. However, plant-based proteins generally miss a few or have a lower...