Guido J E J Hooiveld
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Explore the profile of Guido J E J Hooiveld including associated specialties, affiliations and a list of published articles.
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54
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1299
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Recent Articles
1.
Attema B, Kummu O, Krutakova M, Pavek P, Hakkola J, Hooiveld G, et al.
Arch Toxicol
. 2024 Dec;
99(3):1203-1221.
PMID: 39718591
Propiconazole is a triazole fungicide previously shown to induce triglyceride accumulation in human liver HepaRG cells, potentially via activation of the Pregnane X Receptor (PXR). However, whether propiconazole can disrupt...
2.
Janssen A, van der Lugt B, Duivenvoorde L, Vos A, Bastiaan-Net S, Tomassen M, et al.
Sci Rep
. 2024 Nov;
14(1):26464.
PMID: 39488516
To investigate intestinal health and its potential disruptors in vitro, representative models are required. Human induced pluripotent stem cell (hiPSC)-derived intestinal epithelial cells (IECs) more closely resemble the in vivo...
3.
van Trijp M, Rios-Morales M, Logtenberg M, Keshtkar S, Afman L, Witteman B, et al.
J Agric Food Chem
. 2024 Sep;
72(38):21152-21165.
PMID: 39282870
Galacto-oligosaccharides (GOS) and fructo-oligosaccharides (FOS) are food ingredients that improve human health, but their degradation throughout the human small intestine is not well understood. We studied the breakdown kinetics of...
4.
Deng L, Michielsen C, Vrieling F, Hooiveld G, Stienstra R, Feitsma A, et al.
Clin Nutr
. 2023 Dec;
43(1):232-245.
PMID: 38101314
Background: Intake of high-fat foods raises postprandial plasma triglycerides and inflammatory markers, which may depend on the type of fat ingested. Dairy products are commonly consumed, but not much is...
5.
Elzinga J, Grouls M, Hooiveld G, van der Zande M, Smidt H, Bouwmeester H
Arch Toxicol
. 2023 Jan;
97(3):737-753.
PMID: 36680592
There is a need for standardized in vitro models emulating the functionalities of the human intestinal tract to study human intestinal health without the use of laboratory animals. The Caco-2...
6.
Attema B, Janssen A, Rijkers D, van Schothorst E, Hooiveld G, Kersten S
Mol Metab
. 2022 Sep;
66:101602.
PMID: 36115532
Objective: Perfluoroalkyl substances (PFAS) are man-made chemicals with demonstrated endocrine-disrupting properties. Exposure to perfluorooctanoic acid (PFOA) has been linked to disturbed metabolism via the liver, although the exact mechanism is...
7.
Grouls M, Janssen A, Duivenvoorde L, Hooiveld G, Bouwmeester H, van der Zande M
Sci Rep
. 2022 Aug;
12(1):13988.
PMID: 35977967
Intestinal epithelial cells and the intestinal microbiota are in a mutualistic relationship that is dependent on communication. This communication is multifaceted, but one aspect is communication through compounds produced by...
8.
Malinowska A, Kok D, Steegenga W, Hooiveld G, Chmurzynska A
Eur J Nutr
. 2022 Jun;
61(8):3887-3903.
PMID: 35748920
Purpose: Some dietary habits cluster together, and for this reason it is advised to study the impact of entire dietary patterns on human health, rather than that of individual dietary...
9.
Kulthong K, Hooiveld G, Duivenvoorde L, Estruch I, Bouwmeester H, van der Zande M
Nanotoxicology
. 2022 Jan;
15(9):1233-1252.
PMID: 35077654
Due to the widespread application of food-relevant inorganic nanomaterials, the gastrointestinal tract is potentially exposed to these materials. Gut-on-chip systems are proposed for the investigation of compound toxicity as they...
10.
Sinha N, van Schothorst E, Hooiveld G, Keijer J, Martins Dos Santos V, Suarez-Diez M
BMC Bioinformatics
. 2021 Nov;
22(1):574.
PMID: 34839828
Background: Several computational methods have been developed that integrate transcriptomics data with genome-scale metabolic reconstructions to increase accuracy of inferences of intracellular metabolic flux distributions. Even though existing methods use...