Marion E Brunck
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Explore the profile of Marion E Brunck including associated specialties, affiliations and a list of published articles.
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9
Citations
442
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Recent Articles
1.
Bisht K, Brunck M, Matsumoto T, McGirr C, Nowlan B, Fleming W, et al.
Blood Adv
. 2019 Feb;
3(3):406-418.
PMID: 30733301
In normoxia, hypoxia-inducible transcription factors (HIFs) are rapidly degraded within the cytoplasm as a consequence of their prolyl hydroxylation by oxygen-dependent prolyl hydroxylase domain (PHD) enzymes. We have previously shown...
2.
Deveson I, Brunck M, Blackburn J, Tseng E, Hon T, Clark T, et al.
Cell Syst
. 2018 Feb;
6(2):245-255.e5.
PMID: 29396323
The human transcriptome is so large, diverse, and dynamic that, even after a decade of investigation by RNA sequencing (RNA-seq), we have yet to resolve its true dimensions. RNA-seq suffers...
3.
Steffani-Vallejo J, Brunck M, Acosta-Cruz E, Montiel R, Barona-Gomez F
Stand Genomic Sci
. 2018 Jan;
13:1.
PMID: 29340007
(Karassova V, Weissfeiler J, Kraszanay E, Acta Microbiol Acad Sci Hung 12:275-82, 1965) is a slow-growing nontuberculous species found in environmental niches, and recently evidenced as an opportunistic Human pathogen....
4.
Nowlan B, Futrega K, Brunck M, Walkinshaw G, Flippin L, Doran M, et al.
Exp Hematol
. 2017 May;
52:50-55.e6.
PMID: 28527810
Granulocyte colony-stimulating factor (G-CSF) is used routinely in the clinical setting to mobilize hematopoietic stem progenitor cells (HSPCs) into the patient's blood for collection and subsequent transplantation. However, a significant...
5.
Jacobsen R, Nowlan B, Brunck M, Barbier V, Winkler I, Levesque J
Exp Hematol
. 2015 Nov;
44(3):207-12.e4.
PMID: 26607596
The cytokines granulocyte colony-stimulating factor (G-CSF) and Flt3 ligand (Flt3-L) mobilize hematopoietic stem and progenitor cells into the peripheral blood of primates, humans, and mice. We recently reported that G-CSF...
6.
Schwaber J, Brunck M, Levesque J, Nielsen L
Curr Opin Hematol
. 2015 Nov;
23(1):72-7.
PMID: 26554894
Purpose Of Review: The success of allogeneic haematopoietic stem and progenitor cell (HSPC) transplantations remains inconsistent. Umbilical cord blood (UCB) is a promising source of HSPCs for transplantation, but low...
7.
Clark M, Mercer T, Bussotti G, Leonardi T, Haynes K, Crawford J, et al.
Nat Methods
. 2015 Mar;
12(4):339-42.
PMID: 25751143
We compared quantitative RT-PCR (qRT-PCR), RNA-seq and capture sequencing (CaptureSeq) in terms of their ability to assemble and quantify long noncoding RNAs and novel coding exons across 20 human tissues....
8.
Mercer T, Clark M, Andersen S, Brunck M, Haerty W, Crawford J, et al.
Genome Res
. 2015 Jan;
25(2):290-303.
PMID: 25561518
During the splicing reaction, the 5' intron end is joined to the branchpoint nucleotide, selecting the next exon to incorporate into the mature RNA and forming an intron lariat, which...
9.
Mercer T, Clark M, Crawford J, Brunck M, Gerhardt D, Taft R, et al.
Nat Protoc
. 2014 Apr;
9(5):989-1009.
PMID: 24705597
RNA sequencing (RNAseq) samples the majority of expressed genes infrequently, owing to the large size, complex splicing and wide dynamic range of eukaryotic transcriptomes. This results in sparse sequencing coverage...