Ingrid G Winkler
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Explore the profile of Ingrid G Winkler including associated specialties, affiliations and a list of published articles.
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51
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1779
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Recent Articles
1.
Alexander K, Tseng H, Lao H, Girard D, Barbier V, Ungerer J, et al.
Cell Rep Med
. 2024 Dec;
5(12):101849.
PMID: 39657663
Why severe injury to the central nervous system (CNS) triggers the development of large neurogenic heterotopic ossifications (NHOs) within periarticular muscles remains unknown. We report that spinal cord injury (SCI)...
2.
Uy G, DeAngelo D, Lozier J, Fisher D, Jonas B, Magnani J, et al.
Blood Rev
. 2024 Mar;
65:101184.
PMID: 38493006
E-selectin, a cytoadhesive glycoprotein, is expressed on venular endothelial cells and mediates leukocyte localization to inflamed endothelium, the first step in inflammatory cell extravasation into tissue. Constitutive marrow endothelial E-selectin...
3.
OBrien L, Walpole C, Leal-Rojas I, Shatunova S, Moore A, Winkler I, et al.
Exp Hematol
. 2023 Dec;
130:104134.
PMID: 38052261
Immunodeficient mice bearing human immune systems, or "humanized" chimeric mice, are widely used in basic research, along with the preclinical stages of drug development. Nonobese diabetic-severe combined immunodeficiency (NOD-SCID) IL2Rγ...
4.
Salga M, Samuel S, Tseng H, Gatin L, Girard D, Rival B, et al.
J Bone Miner Res
. 2023 Aug;
38(11):1700-1717.
PMID: 37602772
Neurogenic heterotopic ossifications (NHO) are heterotopic bones that develop in periarticular muscles after severe central nervous system (CNS) injuries. Several retrospective studies have shown that NHO prevalence is higher in...
5.
Tay J, Bisht K, Winkler I, Levesque J
Methods Mol Biol
. 2023 Apr;
2635:43-61.
PMID: 37074656
The erythroblastic island (EBI) is a multicellular functional erythropoietic unit comprising a central macrophage nurturing a rosette of maturing erythroblasts. Since the discovery of EBIs more than half a century...
6.
Starobova H, Alshammari A, Winkler I, Vetter I
J Neurochem
. 2022 Nov;
168(11):3620-3643.
PMID: 36394416
The high prevalence of pain and the at times low efficacy of current treatments represent a significant challenge to healthcare systems worldwide. Effective treatment strategies require consideration of the diverse...
7.
Bisht K, McGirr C, Lee S, Tseng H, Fleming W, Alexander K, et al.
Leukemia
. 2021 Sep;
36(2):333-347.
PMID: 34518644
We show that pro-inflammatory oncostatin M (OSM) is an important regulator of hematopoietic stem cell (HSC) niches in the bone marrow (BM). Treatment of healthy humans and mice with granulocyte...
8.
Levesque J, Summers K, Bisht K, Millard S, Winkler I, Pettit A
Exp Hematol
. 2021 Sep;
103:1-14.
PMID: 34500024
It has recently emerged that tissue-resident macrophages are key regulators of several stem cell niches orchestrating tissue formation during development, as well as postnatally, when they also organize the repair...
9.
Levesque J, Summers K, Millard S, Bisht K, Winkler I, Pettit A
Exp Hematol
. 2021 Jul;
100:12-31.e1.
PMID: 34298116
The bone marrow (BM) contains a mosaic of niches specialized in supporting different maturity stages of hematopoietic stem and progenitor cells such as hematopoietic stem cells and myeloid, lymphoid, and...
10.
Tay J, Barbier V, Helwani F, Price G, Levesque J, Winkler I
Stem Cells
. 2021 Jul;
39(11):1532-1545.
PMID: 34260805
Hematopoietic stem cells (HSCs) with superior reconstitution potential are reported to be enriched in the endosteal compared to central bone marrow (BM) region. To investigate whether specific factors at the...