Marc N Wein
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Explore the profile of Marc N Wein including associated specialties, affiliations and a list of published articles.
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59
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1768
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Recent Articles
1.
Tokavanich N, Chan B, Strauss K, Castro Andrade C, Arai Y, Nagata M, et al.
J Bone Miner Res
. 2025 Mar;
PMID: 40057979
Alveolar bone supports and anchors teeth. The parathyroid hormone-related protein (PTHrP) pathway plays a key role in alveolar bone biology. Salt inducible kinases (SIKs) are important downstream regulators of PTH/PTHrP...
2.
McGarrity S, Ziehr D, Austin-Tse C, Wein M, Chivukula R, Oldham W
Circ Genom Precis Med
. 2024 Sep;
17(5):e004741.
PMID: 39328057
No abstract available.
3.
Gritti I, Wan J, Weeresekara V, Vaz J, Tarantino G, Bryde T, et al.
Cancer Discov
. 2024 Sep;
15(2):382-400.
PMID: 39326063
This work combines functional studies in model systems and examination of human tumor specimens to define a central oncogenic pathway driven by DNAJB1-PRKACA fusions in FLC. DNAJB1-PRKACA-mediated inactivation of the...
4.
Tokavanich N, Chan B, Strauss K, Castro Andrade C, Arai Y, Nagata M, et al.
bioRxiv
. 2024 Sep;
PMID: 39282451
Summary Statement: SIK2/SIK3 deletion in alveolar bone reduces bone formation and mass by impairing osteoblast maturation, unlike in long bones, where it increases bone formation and mass.
5.
Papaioannou G, Sato T, Houghton C, Kotsalidis P, Strauss K, Dean T, et al.
bioRxiv
. 2024 Jul;
PMID: 38979143
Osteocytes are the primary mechano-sensitive cell type in bone. Mechanical loading is sensed across the dendritic projections of osteocytes leading to transient reductions in focal adhesion kinase (FAK) activity. Knowledge...
6.
7.
Al-Mutairi D, Jarragh A, Alsabah B, Wein M, Mohammed W, Alkharafi L
JBMR Plus
. 2024 Apr;
8(5):ziae026.
PMID: 38562913
Osteogenesis imperfecta (OI) is a heterogeneous spectrum of hereditary genetic disorders that cause bone fragility, through various quantitative and qualitative defects of type 1 collagen, a triple helix composed of...
8.
Cung M, Sosa B, Yang H, McDonald M, Matthews B, Vlug A, et al.
J Bone Miner Res
. 2024 Mar;
39(2):106-115.
PMID: 38477743
Artificial intelligence (AI) chatbots utilizing large language models (LLMs) have recently garnered significant interest due to their ability to generate humanlike responses to user inquiries in an interactive dialog format....
9.
Wein M
Dev Cell
. 2024 Jan;
59(2):173-174.
PMID: 38262346
Although mechanical cues are known to influence the postnatal skeleton, the impact of bone cell mechano-transduction on early skeletal development remains less clear. In this issue of Developmental Cell, Collins...
10.
Li J, Hanley L, Powe C, Seiglie J, Haines M, Wein M, et al.
J Clin Transl Sci
. 2023 Nov;
7(1):e238.
PMID: 38028349
Physician parents encounter unique challenges in balancing new parenthood with work responsibilities, especially upon their return from parental leave. We designed a pilot program that incorporated 1:1 parental coaching to...