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Henry M Kronenberg

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Articles 118
Citations 8775
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Recent Articles
1.
Massengale M, Massengale J, Benson C, Baryawno N, Oki T, Steinhauser M, et al.
JCI Insight . 2023 Sep; 8(17). PMID: 37681409
The identity and origin of the stem/progenitor cells for adult joint cartilage repair remain unknown, impeding therapeutic development. Simulating the common therapeutic modality for cartilage repair in humans, i.e., full-thickness...
2.
Baronas J, Bartell E, Eliasen A, Doench J, Yengo L, Vedantam S, et al.
Cell Genom . 2023 May; 3(5):100299. PMID: 37228756
Alterations in the growth and maturation of chondrocytes can lead to variation in human height, including monogenic disorders of skeletal growth. We aimed to identify genes and pathways relevant to...
3.
Fan W, Machado M, Leder B, Beyer L, Garcia E, Kronenberg H, et al.
J Clin Endocrinol Metab . 2022 Sep; 108(1):191-197. PMID: 36056816
Context: Fragility fractures increase risks for future fractures, morbidity, and mortality. Available pharmacotherapy for underlying osteoporosis is safe and effective but underused. Objective: To improve pharmacotherapy rate representing secondary prevention...
4.
Econs M, Selen D, Balza R, Zurkiya O, Kronenberg H, Hung Y
N Engl J Med . 2022 Jun; 386(24):2316-2326. PMID: 35704485
No abstract available.
5.
Daley E, Yoon S, Reyes M, Bruce M, Brooks D, Bouxsein M, et al.
Endocrinology . 2022 Apr; 163(7). PMID: 35460406
Rodent models are commonly used to evaluate parathyroid hormone (PTH) and PTH-related protein (PTHrP) ligands and analogues for their pharmacologic activities and potential therapeutic utility toward diseases of bone and...
6.
Golden E, Zhang F, Selen D, Ebb D, Romo L, Drubach L, et al.
Front Neurol . 2022 Apr; 13:855157. PMID: 35370900
Patients with fibrous dysplasia (FD) often present with craniofacial lesions that affect the trigeminal nerve system. Debilitating pain, headache, and migraine are frequently experienced by FD patients with poor prognosis,...
7.
Wang J, Kamath T, Mazur C, Mirzamohammadi F, Rotter D, Hojo H, et al.
Nat Commun . 2021 Nov; 12(1):6271. PMID: 34725346
Some osteoblasts embed within bone matrix, change shape, and become dendrite-bearing osteocytes. The circuitry that drives dendrite formation during "osteocytogenesis" is poorly understood. Here we show that deletion of Sp7...
8.
Renthal N, Nakka P, Baronas J, Kronenberg H, Hirschhorn J
J Bone Miner Res . 2021 Aug; 36(12):2300-2308. PMID: 34346115
Human adult height reflects the outcome of childhood skeletal growth. Growth plate (epiphyseal) chondrocytes are key determinants of height. As epiphyseal chondrocytes mature and proliferate, they pass through three developmental...
9.
Hallett S, Matsushita Y, Ono W, Sakagami N, Mizuhashi K, Tokavanich N, et al.
Elife . 2021 Jul; 10. PMID: 34309509
Chondrocytes in the resting zone of the postnatal growth plate are characterized by slow cell cycle progression, and encompass a population of parathyroid hormone-related protein (PTHrP)-expressing skeletal stem cells that...
10.
Tang C, Castro Andrade C, OMeara M, Yoon S, Sato T, Brooks D, et al.
Elife . 2021 Jun; 10. PMID: 34160349
Bone formation and resorption are typically coupled, such that the efficacy of anabolic osteoporosis treatments may be limited by bone destruction. The multi-kinase inhibitor YKL-05-099 potently inhibits salt inducible kinases...