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Manoja K Brahma

Explore the profile of Manoja K Brahma including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 438
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Recent Articles
1.
Vandenbempt V, Eski S, Brahma M, Li A, Negueruela J, Bruggeman Y, et al.
iScience . 2024 Jan; 27(1):108694. PMID: 38213620
An altered gut microbiota is associated with type 1 diabetes (T1D), affecting the production of short-chain fatty acids (SCFA) and glucose homeostasis. We previously demonstrated that enhancing serum acetate and...
2.
Ha C, Bakshi S, Brahma M, Potter L, Chang S, Sun Z, et al.
J Am Heart Assoc . 2023 Sep; 12(19):e029898. PMID: 37750556
Background Lifestyle and metabolic diseases influence the severity and pathogenesis of cardiovascular disease through numerous mechanisms, including regulation via posttranslational modifications. A specific posttranslational modification, the addition of -linked β-...
3.
Brahma M, Xiao P, Popa M, Negueruela J, Vandenbempt V, Demine S, et al.
Nutrients . 2022 Sep; 14(18). PMID: 36145242
The loss of functional pancreatic β-cell mass is an important hallmark of both type 1 and type 2 diabetes. The RNA-binding protein NOVA1 is expressed in human and rodent pancreatic...
4.
Elvira B, Vandenbempt V, Bauza-Martinez J, Crutzen R, Negueruela J, Ibrahim H, et al.
Diabetes . 2022 Jan; 71(4):653-668. PMID: 35044456
Type 1 diabetes (T1D) results from autoimmune destruction of β-cells in the pancreas. Protein tyrosine phosphatases (PTPs) are candidate genes for T1D and play a key role in autoimmune disease...
5.
Brahma M, Gilglioni E, Zhou L, Trepo E, Chen P, Gurzov E
Oncogene . 2021 Jul; 40(33):5155-5167. PMID: 34290399
Obesity affects more than 650 million individuals worldwide and is a well-established risk factor for the development of hepatocellular carcinoma (HCC). Oxidative stress can be considered as a bona fide...
6.
Brahma M, Wende A, McCommis K
J Physiol . 2021 Mar; 600(5):1011-1012. PMID: 33644878
No abstract available.
7.
Brahma M, Wende A, McCommis K
J Physiol . 2021 Mar; 600(5):1005-1007. PMID: 33644874
No abstract available.
8.
Brahma M, Ha C, Pepin M, Mia S, Sun Z, Chatham J, et al.
J Am Heart Assoc . 2020 Aug; 9(15):e013039. PMID: 32750298
Background Perturbations in myocardial substrate utilization have been proposed to contribute to the pathogenesis of cardiac dysfunction in diabetic subjects. The failing heart in nondiabetics tends to decrease reliance on...
9.
Wende A, Schell J, Ha C, Pepin M, Khalimonchuk O, Schwertz H, et al.
Diabetes . 2020 May; 69(10):2094-2111. PMID: 32366681
Cardiac glucose uptake and oxidation are reduced in diabetes despite hyperglycemia. Mitochondrial dysfunction contributes to heart failure in diabetes. It is unclear whether these changes are adaptive or maladaptive. To...
10.
Pepin M, Padgett L, McDowell R, Burg A, Brahma M, Holleman C, et al.
Mol Metab . 2018 May; 12:48-61. PMID: 29731256
Objective: Breakthroughs in HIV treatment, especially combination antiretroviral therapy (ART), have massively reduced AIDS-associated mortality. However, ART administration amplifies the risk of non-AIDS defining illnesses including obesity, diabetes, and cardiovascular...