Manoj Duraisingh
Overview
Explore the profile of Manoj Duraisingh including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
363
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0
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Recent Articles
1.
Obaldia 3rd N, Da Silva Filho J, Nunez M, Glass K, Oulton T, Achcar F, et al.
Life Sci Alliance
. 2023 Dec;
7(3).
PMID: 38158220
The malaria parasite remains a major global public health challenge, and no vaccine is approved for use in humans. Here, we assessed whether strain-transcendent immunity can be achieved by repeated...
2.
Kundu P, Naskar D, McKie S, Dass S, Kanjee U, Introini V, et al.
Nat Commun
. 2023 Sep;
14(1):5703.
PMID: 37709739
Tryptophan Rich Antigens (TRAgs) are encoded by a multi-gene family found in all Plasmodium species, but are significantly expanded in P. vivax and closely related parasites. We show that multiple...
3.
Elsworth B, Keroack C, Rezvani Y, Paul A, Barazorda K, Tennessen J, et al.
Res Sq
. 2023 Mar;
PMID: 36909484
Apicomplexan egress from host cells is fundamental to the spread of infection and is poorly characterized in spp., parasites of veterinary importance and emerging zoonoses. Through the use of video...
4.
Vandorpe D, Rivera A, Ganter M, Dankwa S, Wohlgemuth J, Dlott J, et al.
Pflugers Arch
. 2022 Feb;
474(5):553-565.
PMID: 35169901
Paracrine ATP release by erythrocytes has been shown to regulate endothelial cell function via purinergic signaling, and this erythoid-endothelial signaling network is pathologically dysregulated in sickle cell disease. We tested...
5.
Guillen N, Duraisingh M
Curr Opin Microbiol
. 2014 Aug;
20:vii-ix.
PMID: 25081632
No abstract available.
6.
Doumbia S, Ndiaye D, Koita O, Diakite M, Nwakanma D, Coulibaly M, et al.
Acta Trop
. 2011 Dec;
121(3):175-83.
PMID: 22142790
With the paradigm shift from the reduction of morbidity and mortality to the interruption of transmission, the focus of malaria control broadens from symptomatic infections in children ≤5 years of...
7.
Ceesay S, Bojang K, Nwakanma D, Conway D, Koita O, Doumbia S, et al.
Acta Trop
. 2011 Nov;
121(3):166-74.
PMID: 22119584
The study sites for the West African ICEMR are in three countries (The Gambia, Senegal, Mali) and are located within 750 km of each other. In addition, the National Malaria...
8.
Broadbent K, Park D, Wolf A, Van Tyne D, Sims J, Ribacke U, et al.
Genome Biol
. 2011 Jun;
12(6):R56.
PMID: 21689454
Background: Mounting evidence suggests a major role for epigenetic feedback in Plasmodium falciparum transcriptional regulation. Long non-coding RNAs (lncRNAs) have recently emerged as a new paradigm in epigenetic remodeling. We...
9.
Barker Jr R, Urgaonkar S, Mazitschek R, Celatka C, Skerlj R, Cortese J, et al.
Antimicrob Agents Chemother
. 2011 Mar;
55(6):2612-22.
PMID: 21422215
This study characterizes aminoindole molecules that are analogs of Genz-644442. Genz-644442 was identified as a hit in a screen of ~70,000 compounds in the Broad Institute's small-molecule library and the...
10.
Booker M, Bastos C, Kramer M, Barker Jr R, Skerlj R, Sidhu A, et al.
J Biol Chem
. 2010 Aug;
285(43):33054-33064.
PMID: 20702404
Plasmodium falciparum, the causative agent of the most deadly form of human malaria, is unable to salvage pyrimidines and must rely on de novo biosynthesis for survival. Dihydroorotate dehydrogenase (DHODH)...