Malcolm G Parker
Overview
Explore the profile of Malcolm G Parker including associated specialties, affiliations and a list of published articles.
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51
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2352
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Recent Articles
1.
Morganstein D, Parker M
Expert Rev Endocrinol Metab
. 2018 Oct;
2(6):797-807.
PMID: 30290475
Understanding the molecular regulation of metabolism will lead to a better understanding of the pathogenesis and treatment of common metabolic conditions, including obesity and diabetes. Nuclear receptors are a family...
2.
Blondrath K, Steel J, Katsouri L, Ries M, Parker M, Christian M, et al.
Neurobiol Aging
. 2016 Sep;
47:180-191.
PMID: 27614112
The receptor interacting protein-140 (RIP140) is a cofactor for several nuclear receptors and has been involved in the regulation of metabolic and inflammatory genes. We hypothesize that RIP140 may also...
3.
Barneda D, Planas-Iglesias J, Gaspar M, Mohammadyani D, Prasannan S, Dormann D, et al.
Elife
. 2015 Nov;
4:e07485.
PMID: 26609809
Maintenance of energy homeostasis depends on the highly regulated storage and release of triacylglycerol primarily in adipose tissue, and excessive storage is a feature of common metabolic disorders. CIDEA is...
4.
Nikolopoulou E, Papacleovoulou G, Jean-Alphonse F, Grimaldi G, Parker M, Hanyaloglu A, et al.
J Lipid Res
. 2014 Oct;
55(12):2479-90.
PMID: 25325755
Arachidonic acid (AA) is a major PUFA that has been implicated in the regulation of adipogenesis. We examined the effect of a short exposure to AA at different stages of...
5.
Rosell M, Nevedomskaya E, Stelloo S, Nautiyal J, Poliandri A, Steel J, et al.
Cancer Res
. 2014 Aug;
74(19):5469-79.
PMID: 25145671
RIP140 is a transcriptional coregulator involved in energy homeostasis, ovulation, and mammary gland development. Although conclusive evidence is lacking, reports have implicated a role for RIP140 in breast cancer. Here,...
6.
Rosell M, Kaforou M, Frontini A, Okolo A, Chan Y, Nikolopoulou E, et al.
Am J Physiol Endocrinol Metab
. 2014 Feb;
306(8):E945-64.
PMID: 24549398
Brown adipocytes dissipate energy, whereas white adipocytes are an energy storage site. We explored the plasticity of different white adipose tissue depots in acquiring a brown phenotype by cold exposure....
7.
Kiskinis E, Chatzeli L, Curry E, Kaforou M, Frontini A, Cinti S, et al.
Mol Endocrinol
. 2014 Feb;
28(3):344-56.
PMID: 24479876
Receptor-interacting protein 140 (RIP140) is a corepressor of nuclear receptors that is highly expressed in adipose tissues. We investigated the role of RIP140 in conditionally immortal preadipocyte cell lines prepared...
8.
Nautiyal J, Christian M, Parker M
Trends Endocrinol Metab
. 2013 Jun;
24(9):451-9.
PMID: 23742741
Nuclear receptors (NRs) regulate tissue development and function by controlling transcription from distinct sets of genes in response to fluctuating levels of hormones or cues that modulate receptor activity. Such...
9.
Nautiyal J, Steel J, Mane M, Oduwole O, Poliandri A, Alexi X, et al.
Development
. 2013 Feb;
140(5):1079-89.
PMID: 23404106
Nuclear receptor interacting protein (Nrip1), also known as RIP140, is a co-regulator for nuclear receptors that plays an essential role in ovulation by regulating the expression of the epidermal growth...
10.
Percharde M, Lavial F, Ng J, Kumar V, Tomaz R, Martin N, et al.
Genes Dev
. 2012 Sep;
26(20):2286-98.
PMID: 23019124
Embryonic stem cell (ESC) pluripotency depends on a well-characterized gene regulatory network centered on Oct4, Sox2, and Nanog. In contrast, little is known about the identity of the key coregulators...