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Neurobiology of Aging

Neurobiology of Aging is a peer-reviewed scientific journal that focuses on the study of age-related changes in the structure and function of the nervous system. It publishes research articles, reviews, and commentaries that explore the molecular, cellular, and physiological aspects of neurodegenerative diseases, cognitive decline, and aging-related neurological disorders. The journal aims to advance our understanding of the aging brain and contribute to the development of effective interventions and treatments for age-related neurological conditions.

Details
Abbr. Neurobiol Aging
Publisher Elsevier
Start 1980
End Continuing
Frequency Monthly, 2006-
p-ISSN 0197-4580
e-ISSN 1558-1497
Country United States
Language English
Metrics
h-index / Ranks: 605 212
SJR / Ranks: 1986 1488
CiteScore / Ranks: 1928 8.70
JIF / Ranks: 2095 4.2
Recent Articles
1.
Lavrova A, Pham N, Reid R, Boeve B, Knopman D, Petersen R, et al.
Neurobiol Aging . 2025 Mar; 150:97-108. PMID: 40088623
Transactive response DNA-binding protein 43 kDa (TDP-43) deposition is linked to regional brain atrophy in Alzheimer's disease (AD), but diffusion changes associated with AD-related TDP-43 proteinopathy remain underexplored. This study...
2.
Rysop A, Williams K, Schmitt L, Meinzer M, Obleser J, Hartwigsen G
Neurobiol Aging . 2025 Mar; 150:109-121. PMID: 40088622
Speech comprehension in noisy environments constitutes a critical challenge in everyday life and affects people of all ages. This challenging listening situation can be alleviated using semantic context to predict...
3.
Tremblay S, Nathan Spreng R, Wearn A, Alasmar Z, Pirhadi A, Tardif C, et al.
Neurobiol Aging . 2025 Mar; 150:80-96. PMID: 40086421
Early detection of pathological changes in Alzheimer's disease (AD) has garnered significant attention in the last few decades as interventions aiming to prevent progression will likely be most effective when...
4.
Bell K, Chrysostomou V, Karlsson M, Jones B, Williams P, Crowston J
Neurobiol Aging . 2025 Mar; 150:69-79. PMID: 40073716
Increasing age and elevated intraocular pressure (IOP) are the two major risk factors for glaucoma, the most common cause of irreversible blindness worldwide. Accumulating evidence is pointing to metabolic failure...
5.
Van Malderen S, Hehl M, Nuyts M, Verstraelen S, Heemels R, Hardwick R, et al.
Neurobiol Aging . 2025 Mar; 150:53-68. PMID: 40068243
Age-related reductions in cerebellar integrity predict motor impairments in older adults (OA), but the contribution of cerebro-cerebellar interactions to these impairments remains unclear. Understanding these interactions could reveal underlying mechanisms...
6.
Singh-Reilly N, Pham N, Graff-Radford J, Machulda M, Spychalla A, Senjem M, et al.
Neurobiol Aging . 2025 Mar; 150:44-52. PMID: 40056539
Dementia with Lewy bodies (DLB) and posterior cortical atrophy (PCA) are neurodegenerative disorders that can overlap clinically and in patterns of regional hypometabolism and show elevated white matter hyperintensity (WMH)...
7.
Qiang Q, Skudder-Hill L, Toyota T, Huang Z, Wei W, Adachi H
Neurobiol Aging . 2025 Mar; 150:9-18. PMID: 40043469
At autopsy, around half of the Alzheimer's disease (AD) brains exhibit Lewy body pathology, and the main component of Lewy body pathology is α-synuclein aggregates. This study investigated the prevalence...
8.
Martins Y, Cardinali C, Torrao A
Neurobiol Aging . 2025 Mar; 150:19-43. PMID: 40043468
Astrocytes are neuromodulator cells. Their complex and dynamic morphology regulates neuronal signaling, synaptic plasticity, and neurogenesis. The impact of aging on astrocyte morphology is still under ongoing debate. Therefore, this...
9.
Ekenze O, Seiler S, Pinheiro A, DeCarli C, Parva P, Habes M, et al.
Neurobiol Aging . 2025 Mar; 150:1-8. PMID: 40043467
MRI visible perivascular spaces (PVS) are associated with cognitive impairment and dementia, which are also associated with disrupted network connectivity. PVS may relate to dementia risk through disruption in brain...
10.
Caulfield M, Vander Werp M, Stancati J, Collier T, Sortwell C, Sandoval I, et al.
Neurobiol Aging . 2025 Feb; 149:54-66. PMID: 40010015
We previously demonstrated that viral vector-mediated striatal Ca1.3 calcium channel downregulation in young adult (3mo) male parkinsonian rats provides uniform, robust protection against levodopa-induced dyskinesias (LID). Acknowledging the association of...