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Maarten Coorens

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Citations 417
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Recent Articles
1.
Ormala-Tiznado A, Allander L, Maatallah M, Kabir M, Brisse S, Sandegren L, et al.
Microbiol Spectr . 2024 Jan; 12(2):e0403622. PMID: 38205958
Extensively drug-resistant (XDR) inflict a notable burden on healthcare worldwide. Of specific concern are strains producing carbapenem-hydrolyzing enzymes, as the therapeutic options for these strains are still very limited. Specific...
2.
Kk S, Wranne M, Sewunet T, Ekedahl E, Coorens M, Tangkoskul T, et al.
JAC Antimicrob Resist . 2023 Feb; 5(1):dlad004. PMID: 36743530
Objectives: Colistin is a last-resort antibiotic, but there has been a rapid increase in colistin resistance, threatening its use in the treatment of infections with carbapenem-resistant (CRE). Plasmid-mediated colistin resistance,...
3.
Soratto T, Darban H, Bjerkner A, Coorens M, Albert J, Allander T, et al.
Microbiol Resour Announc . 2020 Aug; 9(35). PMID: 32855259
Here, we report four coding-complete severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome sequences from Stockholm, Sweden, sampled in late April 2020. A rare variant at bp 23463 of the...
4.
Scheenstra M, van Harten R, Veldhuizen E, Haagsman H, Coorens M
Front Immunol . 2020 Jun; 11:1137. PMID: 32582207
Cathelicidins are short cationic peptides that are part of the innate immune system. At first, these peptides were studied mostly for their direct antimicrobial killing capacity, but nowadays they are...
5.
Froding I, Hasan B, Sylvin I, Coorens M, Naucler P, Giske C
Antimicrob Agents Chemother . 2020 May; 64(8). PMID: 32423949
Invasive infections due to extended-spectrum-β-lactamase- and pAmpC-producing (ESBL/pAmpC-EC) are an important cause of morbidity, often caused by the high-risk clone sequence type (ST131) and isolates classified as extraintestinal pathogenic (ExPEC)....
6.
Al-Adwani S, Wallin C, Balhuizen M, Veldhuizen E, Coorens M, Landreh M, et al.
Sci Rep . 2020 Feb; 10(1):2376. PMID: 32047184
Arginine residues of the antimicrobial peptide LL-37 can be citrullinated by peptidyl arginine deiminases, which reduce the positive charge of the peptide. Notably, citrullinated LL-37 has not yet been detected...
7.
Karadottir H, Coorens M, Liu Z, Wang Y, Agerberth B, Giske C, et al.
Infect Immun . 2019 Oct; 88(1). PMID: 31611270
Antibiotic-resistant isolates constitute a great clinical challenge. One important resistance mechanism in is the metallo-β-lactamases (MBLs), which require zinc for their function. Thus, zinc chelation could be a strategy to...
8.
Coorens M, Rao A, Grafe S, Unelius D, Lindforss U, Agerberth B, et al.
J Biol Chem . 2019 Feb; 294(15):6027-6041. PMID: 30782844
and are opportunistic pathogens that are commonly associated with infections at mucosal surfaces, such as the lung or the gut. The host response against these types of infections includes the...
9.
Schneider V, Coorens M, Tjeerdsma-van Bokhoven J, Posthuma G, van Dijk A, Veldhuizen E, et al.
mSphere . 2017 Nov; 2(6). PMID: 29104934
Chicken cathelicidin-2 (CATH-2) is a broad-spectrum antimicrobial host defense peptide (HDP) that may serve as a paradigm for the development of new antimicrobial agents. While previous studies have elucidated the...
10.
Coorens M, Banaschewski B, Baer B, Yamashita C, van Dijk A, Haagsman H, et al.
Infect Immun . 2017 Sep; 85(12). PMID: 28947647
The development of antibiotic resistance by is a major concern in the treatment of bacterial pneumonia. In the search for novel anti-infective therapies, the chicken-derived peptide cathelicidin-2 (CATH-2) has emerged...