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Maaike R Scheenstra

Explore the profile of Maaike R Scheenstra including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 300
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Recent Articles
1.
Chaye M, Gasan T, Ozir-Fazalalikhan A, Scheenstra M, Zawistowska-Deniziak A, van Hengel O, et al.
PLoS Negl Trop Dis . 2023 Jun; 17(6):e0011344. PMID: 37363916
During chronic schistosome infections, a complex regulatory network is induced to regulate the host immune system, in which IL-10-producing regulatory B (Breg) cells play a significant role. Schistosoma mansoni soluble...
2.
van Dijk A, Anten J, Bakker A, Evers N, Hoekstra A, Chang J, et al.
Front Immunol . 2022 Aug; 13:777530. PMID: 35958593
Trained innate immunity can be induced in human macrophages by microbial ligands, but it is unknown if exposure to endogenous alarmins such as cathelicidins can have similar effects. Previously, we...
3.
van Harten R, Tjeerdsma-van Bokhoven J, de Greeff A, Balhuizen M, van Dijk A, Veldhuizen E, et al.
J Adv Res . 2022 Feb; 36:101-112. PMID: 35127168
Introduction: Due to the increase of antibiotic resistant bacterial strains, there is an urgent need for development of alternatives to antibiotics. Cathelicidins can be such an alternative to antibiotics having...
4.
van Harten R, Veldhuizen E, Haagsman H, Scheenstra M
Vet Immunol Immunopathol . 2021 Dec; 244:110369. PMID: 34954638
Infectious diseases in pigs cause monetary loss to farmers and pose a zoonotic risk. Therefore, it is important to obtain more porcine specific immunological knowledge as a measure to protect...
5.
Scheenstra M, Martinez-Botia P, Acebes-Huerta A, Brouwer R, Caballero-Sanchez N, Gillemans N, et al.
J Leukoc Biol . 2020 Dec; PMID: 33289106
Dendritic cells (DCs) are key immune modulators and are able to mount immune responses or tolerance. DC differentiation and activation imply a plethora of molecular and cellular responses, including transcriptional...
6.
Peng L, Scheenstra M, van Harten R, Haagsman H, Veldhuizen E
Vet Res . 2020 Sep; 51(1):122. PMID: 32972448
Cathelicidins (CATHs) play an important role in the innate immune response against microbial infections. Among the four chicken cathelicidins, CATH-B1 is studied the least. In this study, the effect of...
7.
Scheenstra M, van Harten R, Veldhuizen E, Haagsman H, Coorens M
Front Immunol . 2020 Jun; 11:1137. PMID: 32582207
Cathelicidins are short cationic peptides that are part of the innate immune system. At first, these peptides were studied mostly for their direct antimicrobial killing capacity, but nowadays they are...
8.
Kraaij M, van Dijk A, Scheenstra M, van Harten R, Haagsman H, Veldhuizen E
Protein Pept Lett . 2019 Aug; 27(1):60-66. PMID: 31362652
Background: Cathelicidins are a family of Host Defense Peptides (HDPs), that play an important role in the innate immune response. They exert both broad-spectrum antimicrobial activity against pathogens, and strong...
9.
Scheenstra M, van den Belt M, Tjeerdsma-van Bokhoven J, Schneider V, Ordonez S, van Dijk A, et al.
Sci Rep . 2019 Mar; 9(1):4780. PMID: 30886247
Host defense peptides (HDPs) play a pivotal role in innate immunity and have, in addition to antimicrobial activity, also important immunomodulatory functions. Bacteria are less likely to develop resistance against...
10.
Gao J, Scheenstra M, van Dijk A, Veldhuizen E, Haagsman H
Vet Immunol Immunopathol . 2018 May; 200:7-15. PMID: 29776615
Background: Macrophages play an important role in the innate immune system as part of the mononuclear phagocyte system (MPS). They have a pro-inflammatory signature (M1-polarized macrophages) or anti-inflammatory signature (M2-polarized...