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Edwin J A Veldhuizen

Explore the profile of Edwin J A Veldhuizen including associated specialties, affiliations and a list of published articles. Areas
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Articles 95
Citations 1990
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Recent Articles
1.
Kunchala S, van Dijk A, Veldhuizen E, Haagsman H, Orgeig S
Philos Trans R Soc Lond B Biol Sci . 2025 Feb; 380(1920):20230425. PMID: 40010397
The common avian origin of many zoonotic infections and epidemics warrants investigation into the mechanism of respiratory surface protection in reservoir species such as birds. Our recent molecular investigations on...
2.
Silva-Lagos L, Ijaz A, Buwalda P, Kassai S, Klostermann C, Leemhuis H, et al.
Carbohydr Polym . 2024 Dec; 350:122980. PMID: 39647934
Isomalto/malto-polysaccharides (IMMPs) are α-glucans with prebiotic potential used as food ingredients. However, their ability to exert direct cellular effects remains unknown. IMMPs may enhance immunity by activating toll-like receptors (TLRs),...
3.
Ijaz A, Pols N, Abboud K, Rutten V, Broere F, Schols H, et al.
Int J Biol Macromol . 2024 Dec; 286():138344. PMID: 39638205
The restrictions on excessive use of antimicrobials in the poultry industry have led to the search for alternative strategies including nutritional interventions to enhance gut health with the ultimate aim...
4.
Pashaie F, Hoornweg T, Bikker F, Veenendaal T, Broere F, Veldhuizen E
Virus Res . 2024 Nov; 350:199496. PMID: 39528011
Porcine epidemic diarrhea virus (PEDV) is a harmful coronavirus infecting pigs, which is resulting in substantial financial losses in the global pig industry. The lack of effective vaccines or treatments...
5.
Javed A, Oedairadjsingh T, Ludwig I, Wood T, Martin N, Broere F, et al.
Mol Immunol . 2024 Aug; 173:100-109. PMID: 39094445
Antimicrobial peptides (AMPs) are a promising alternative to antibiotics in the fight against multi-drug resistant and immune system-evading bacterial infections. Protegrins are porcine cathelicidins which have been identified in porcine...
6.
Lyu Q, Veldhuizen E, Ludwig I, Rutten V, van Eden W, Sijts A, et al.
PLoS One . 2023 Nov; 18(11):e0292757. PMID: 37939066
Macrophages can reversibly polarize into multiple functional subsets depending on their micro-environment. Identification and understanding the functionality of these subsets is relevant for the study of immune‑related diseases. However, knowledge...
7.
Javed A, Balhuizen M, Pannekoek A, Bikker F, Heesterbeek D, Haagsman H, et al.
Pharmaceuticals (Basel) . 2023 Oct; 16(10). PMID: 37895956
The binding of Host Defense Peptides (HDPs) to the endotoxin of Gram-negative bacteria has important unsolved aspects. For most HDPs, it is unclear if binding is part of the antibacterial...
8.
Ijaz A, Broere F, Rutten V, Jansen C, Veldhuizen E
Dev Comp Immunol . 2023 Aug; 149:105047. PMID: 37625470
Natural killer (NK) cells are cytotoxic lymphocytes that are present in the circulation but also in many organs including spleen and gut, where they play an important role in the...
9.
Javed A, Slingerland C, Wood T, Martin N, Broere F, Weingarth M, et al.
ACS Infect Dis . 2023 Feb; 9(3):518-526. PMID: 36790385
Peptide antibiotics have gathered attention given the urgent need to discover antimicrobials with new mechanisms of action. Their extended role as immunomodulators makes them interesting candidates for the development of...
10.
Kunchala S, van Dijk A, Veldhuizen E, Donnellan S, Haagsman H, Orgeig S
Dev Comp Immunol . 2022 Oct; 139:104582. PMID: 36306971
The air-liquid interface of the mammalian lung is lined with pulmonary surfactants, a mixture of specific proteins and lipids that serve a dual purpose-enabling air-breathing and protection against pathogens. In...