M S Parmacek
Overview
Explore the profile of M S Parmacek including associated specialties, affiliations and a list of published articles.
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36
Citations
1718
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Recent Articles
1.
Li W, Waldo K, Linask K, Chen T, Wessels A, Parmacek M, et al.
Development
. 2002 Apr;
129(8):2031-42.
PMID: 11934868
Connexin43 knockout mice die neonatally from conotruncal heart malformation and outflow obstruction. Previous studies have indicated the involvement of neural crest perturbations in these cardiac anomalies. We provide evidence for...
2.
Strobeck M, Kim S, Zhang J, Clendenin C, Du K, Parmacek M
J Biol Chem
. 2001 Mar;
276(19):16418-24.
PMID: 11279108
Serum response factor (SRF) plays an important role in regulating smooth muscle cell (SMC) development and differentiation. To understand the molecular mechanisms underlying the activity of SRF in SMCs, the...
3.
4.
Zhang J, Kim S, Helmke B, Yu W, Du K, Lu M, et al.
Mol Cell Biol
. 2001 Feb;
21(4):1336-44.
PMID: 11158319
SM22alpha is a 22-kDa smooth muscle cell (SMC) lineage-restricted protein that physically associates with cytoskeletal actin filament bundles in contractile SMCs. To examine the function of SM22alpha, gene targeting was...
5.
Akyurek L, Yang Z, Aoki K, San H, Nabel G, Parmacek M, et al.
Mol Med
. 2001 Jan;
6(11):983-91.
PMID: 11147575
Background: Gene transfer into vascular smooth muscle cells (vsmcs) holds promise for studying the pathogenesis of arterial disorders. However, a potential limitation of vectors with heterologous promoters is organ toxicity...
6.
Aoki K, Akyurek L, San H, Leung K, Parmacek M, Nabel E, et al.
Mol Ther
. 2000 Aug;
1(6):555-65.
PMID: 10933980
Gene transfer of Fas ligand (CD95L) using adenoviral vectors has been shown to generate apoptotic responses and potent inflammatory reactions that can be used to induce the regression of malignancies...
7.
Camoretti-Mercado B, Liu H, Halayko A, Forsythe S, KYLE J, Li B, et al.
J Biol Chem
. 2000 Jun;
275(39):30387-93.
PMID: 10866994
Prolonged serum deprivation induces a structurally and functionally contractile phenotype in about 1/6 of cultured airway myocytes, which exhibit morphological elongation and accumulate abundant contractile apparatus-associated proteins. We tested the...
8.
Morrisey E, Musco S, Chen M, Lu M, Leiden J, Parmacek M
J Biol Chem
. 2000 Apr;
275(26):19949-54.
PMID: 10779506
Gene targeting studies have demonstrated that the zinc finger transcription factor GATA-6 lies upstream in a transcriptional cascade that controls differentiation of the visceral endoderm. To understand the function of...
9.
Morrisey E, Tang Z, Sigrist K, Lu M, Jiang F, Ip H, et al.
Genes Dev
. 1998 Dec;
12(22):3579-90.
PMID: 9832509
GATA6 belongs to a family of zinc finger transcription factors that play important roles in transducing nuclear events that regulate cellular differentiation and embryonic morphogenesis in vertebrate species. To examine...
10.
Kim S, Lin H, Barr E, Chu L, Leiden J, Parmacek M
J Clin Invest
. 1997 Sep;
100(5):1006-14.
PMID: 9276717
Gene transfer using replication-defective adenoviruses (RDAd) holds promise for the treatment of vascular proliferative disorders, but is potentially limited by the capacity of these viruses to infect multiple cell lineages....