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Current Topics in Developmental Biology

Current Topics in Developmental Biology is a scientific journal, published by Elsevier since 1966 in English. The journal's country of origin is United States and its primary focus areas are biology and reproductive medicine.

Details
Abbr. Curr Top Dev Biol
Publisher Elsevier
Start 1966
End Continuing
Frequency Five issues yearly, <2003->
p-ISSN 0070-2153
e-ISSN 1557-8933
Country United States
Language English
Recent Articles
1.
Blaner W, Paik J, Brun P, Golczak M
Curr Top Dev Biol . 2025 Jan; 161:89-111. PMID: 39870440
Alterations in tissue expression levels of both retinol-binding protein 2 (RBP2) and retinol-binding protein 4 (RBP4) have been associated with metabolic disease, specifically with obesity, glucose intolerance and hepatic steatosis....
2.
Perrotta G, Condrea D, Ghyselinck N
Curr Top Dev Biol . 2025 Jan; 161():59-88. PMID: 39870439
In mammals, differentiation of germ cells is crucial for sexual reproduction, involving complex signaling pathways and environmental cues defined by the somatic cells of the gonads. This review examines the...
3.
Nakamura M, Sandell L
Curr Top Dev Biol . 2025 Jan; 161():33-57. PMID: 39870438
Retinoic acid (RA) signaling plays multiple essential roles in development of the head and face. Animal models with mutations in genes involved in RA signaling have enabled understanding of craniofacial...
4.
Bandara S, von Lintig J
Curr Top Dev Biol . 2025 Jan; 161():319-348. PMID: 39870437
Animals perceiving light through visual pigments have evolved pathways for absorbing, transporting, and metabolizing the precursors essential for synthesis of their retinylidene chromophores. Over the past decades, our understanding of...
5.
Bandral M, Sussel L, Lorberbaum D
Curr Top Dev Biol . 2025 Jan; 161():297-318. PMID: 39870436
All-trans retinoic acid (ATRA) signaling is essential in numerous different biological contexts. This review highlights the diverse roles of ATRA during development, function, and diseases of the pancreas. ATRA is...
6.
Engfer Z, Palczewski K
Curr Top Dev Biol . 2025 Jan; 161():235-296. PMID: 39870435
Vitamin A (all-trans-retinol; at-Rol) and its derivatives, known as retinoids, have been adopted by vertebrates to serve as visual chromophores and signaling molecules, particularly in the eye/retina. Few tissues rely...
7.
Kane M
Curr Top Dev Biol . 2025 Jan; 161():201-233. PMID: 39870434
Retinoids, particularly all-trans-retinoic acid (ATRA), play crucial roles in various physiological processes, including development, immune response, and reproduction, by regulating gene transcription through nuclear receptors. This review explores the biosynthetic...
8.
Isoherranen N, Wen Y
Curr Top Dev Biol . 2025 Jan; 161():167-200. PMID: 39870433
The active metabolite of vitamin A, all-trans-retinoic acid (atRA), is critical for maintenance of many cellular processes. Although the enzymes that can synthesize and clear atRA in mammals have been...
9.
Havel S, Griswold M
Curr Top Dev Biol . 2025 Jan; 161():143-166. PMID: 39870432
For mammalian spermatogenesis to proceed normally, it is essential that the population of testicular progenitor cells, A undifferentiated spermatogonia (A), undergoes differentiation during the A to A1 transition that occurs...
10.
Fainsod A, Vadigepalli R
Curr Top Dev Biol . 2025 Jan; 161():113-141. PMID: 39870431
All-trans retinoic acid (ATRA) signaling is a major pathway regulating numerous differentiation, proliferation, and patterning processes throughout life. ATRA biosynthesis depends on the nutritional availability of vitamin A and other...