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Ludmila Alexandrova

Explore the profile of Ludmila Alexandrova including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 109
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Recent Articles
1.
Nshanian M, Gruber J, Geller B, Chleilat F, Lancaster S, White S, et al.
Nat Metab . 2025 Jan; 7(1):196-211. PMID: 39789354
The short-chain fatty acids (SCFAs) propionate and butyrate have beneficial health effects, are produced in large amounts by microbial metabolism and have been identified as unique acyl lysine histone marks....
2.
Rodrigues A, Chernikova S, Wang Y, Trinh T, Solow-Cordero D, Alexandrova L, et al.
J Neurooncol . 2024 Apr; 168(1):125-138. PMID: 38563850
Purpose: Triple-negative breast cancer (TNBC) often metastasizes to the central nervous system (CNS) and has the highest propensity among breast cancer subtypes to develop leptomeningeal disease (LMD). LMD is a...
3.
Rodrigues A, Chernikova S, Wang Y, Trinh T, Solow-Cordero D, Alexandrova L, et al.
Res Sq . 2024 Feb; PMID: 38405839
Purpose: Triple-negative breast cancer (TNBC) is an aggressive subtype that often metastasizes to the brain. Leptomeningeal disease (LMD), a devastating brain metastasis common in TNBC, has limited treatment options. We...
4.
Nshanian M, Gruber J, Geller B, Chleilat F, Lancaster S, White S, et al.
bioRxiv . 2024 Jan; PMID: 38293216
The short-chain fatty acids (SCFA) propionate and butyrate have beneficial health effects, are produced in large amounts by microbial metabolism and have been identified as unique acyl lysine histone marks....
5.
Bakooshli M, Wang Y, Monti E, Su S, Kraft P, Nalbandian M, et al.
Sci Transl Med . 2023 Oct; 15(717):eadg1485. PMID: 37820010
To date, there are no approved treatments for the diminished strength and paralysis that result from the loss of peripheral nerve function due to trauma, heritable neuromuscular diseases, or aging....
6.
Alexandrova L, Haque F, Rodriguez P, Marrazzo A, Grembi J, Ramachandran V, et al.
J Infect Dis . 2019 Jun; 220(10):1655-1666. PMID: 31192364
Background: A first step to combating antimicrobial resistance in enteric pathogens is to establish an objective assessment of antibiotic exposure. Our goal was to develop and evaluate a liquid chromatography-ion...
7.
Going C, Alexandrova L, Lau K, Yeh C, Feldman D, Pitteri S
Breast Cancer Res Treat . 2017 Nov; 167(3):797-802. PMID: 29116467
Purpose: 27-hydroxycholesterol (27HC), an endogenous selective estrogen receptor modulator (SERM), drives the growth of estrogen receptor-positive (ER+) breast cancer. 1,25-dihydroxyvitamin D (1,25(OH)D), the active metabolite of vitamin D, is known...
8.
Orcholski M, Khurshudyan A, Shamskhou E, Yuan K, Chen I, Kodani S, et al.
Am J Physiol Lung Cell Mol Physiol . 2017 May; 313(2):L252-L266. PMID: 28473326
Pulmonary arterial hypertension is a complication of methamphetamine use (METH-PAH), but the pathogenic mechanisms are unknown. Given that cytochrome P450 2D6 (CYP2D6) and carboxylesterase 1 (CES1) are involved in metabolism...
9.
Matyugina E, Khandazhinskaya A, Chernousova L, Andreevskaya S, Smirnova T, Chizhov A, et al.
Bioorg Med Chem . 2012 Oct; 20(22):6680-6. PMID: 23062712
A series of new carbocyclic uracil derivatives were synthesized and evaluated as potential antituberculosis agents. Racemic 1-[4'-hydroxy-2'-cyclopenten-1'-yl]-5-tetradecynyluracil completely inhibited the growth of Mycobacterium tuberculosis H37Rv in vitro at a concentration...
10.
Chandran S, Li H, Dong W, Krasinska K, Adams C, Alexandrova L, et al.
J Biol Chem . 2011 Sep; 286(43):37830-40. PMID: 21900244
Regulation of epithelial Na(+) channel (ENaC)-mediated transport in the distal nephron is a critical determinant of blood pressure in humans. Aldosterone via serum and glucocorticoid kinase 1 (SGK1) stimulates ENaC...