Lucas Treps
Overview
Explore the profile of Lucas Treps including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
46
Citations
3257
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
21.
Rohlenova K, Goveia J, Garcia-Caballero M, Subramanian A, Kalucka J, Treps L, et al.
Cell Metab
. 2020 Apr;
31(4):862-877.e14.
PMID: 32268117
Endothelial cell (EC) metabolism is an emerging target for anti-angiogenic therapy in tumor angiogenesis and choroidal neovascularization (CNV), but little is known about individual EC metabolic transcriptomes. By single-cell RNA...
22.
Goveia J, Rohlenova K, Taverna F, Treps L, Conradi L, Pircher A, et al.
Cancer Cell
. 2020 Mar;
37(3):421.
PMID: 32183954
No abstract available.
23.
Kalucka J, de Rooij L, Goveia J, Rohlenova K, Dumas S, Meta E, et al.
Cell
. 2020 Feb;
180(4):764-779.e20.
PMID: 32059779
The heterogeneity of endothelial cells (ECs) across tissues remains incompletely inventoried. We constructed an atlas of >32,000 single-EC transcriptomes from 11 mouse tissues and identified 78 EC subclusters, including Aqp7...
24.
Goveia J, Rohlenova K, Taverna F, Treps L, Conradi L, Pircher A, et al.
Cancer Cell
. 2020 Jan;
37(1):21-36.e13.
PMID: 31935371
Heterogeneity of lung tumor endothelial cell (TEC) phenotypes across patients, species (human/mouse), and models (in vivo/in vitro) remains poorly inventoried at the single-cell level. We single-cell RNA (scRNA)-sequenced 56,771 endothelial...
25.
Declercq M, Treps L
FEBS J
. 2019 May;
286(12):2273-2276.
PMID: 31081213
The RAF/MEK/ERK signal transduction pathway is commonly deregulated in cancer and is activated by various stimuli regulating a variety of cell responses. In wild-type endothelial cells, upon permeability stimuli, ROKα,...
26.
Khan S, Taverna F, Rohlenova K, Treps L, Geldhof V, de Rooij L, et al.
Nucleic Acids Res
. 2018 Oct;
47(D1):D736-D744.
PMID: 30357379
Endothelial cells (ECs) line blood vessels, regulate homeostatic processes (blood flow, immune cell trafficking), but are also involved in many prevalent diseases. The increasing use of high-throughput technologies such as...
27.
Eelen G, Dubois C, Cantelmo A, Goveia J, Bruning U, DeRan M, et al.
Nature
. 2018 Aug;
561(7721):63-69.
PMID: 30158707
Glutamine synthetase, encoded by the gene GLUL, is an enzyme that converts glutamate and ammonia to glutamine. It is expressed by endothelial cells, but surprisingly shows negligible glutamine-synthesizing activity in...
28.
Kalucka J, Bierhansl L, Conchinha N, Missiaen R, Elia I, Bruning U, et al.
Cell Metab
. 2018 Aug;
28(6):881-894.e13.
PMID: 30146488
Little is known about the metabolism of quiescent endothelial cells (QECs). Nonetheless, when dysfunctional, QECs contribute to multiple diseases. Previously, we demonstrated that proliferating endothelial cells (PECs) use fatty acid...
29.
Bruning U, Morales-Rodriguez F, Kalucka J, Goveia J, Taverna F, Queiroz K, et al.
Cell Metab
. 2018 Aug;
28(6):866-880.e15.
PMID: 30146486
The role of fatty acid synthesis in endothelial cells (ECs) remains incompletely characterized. We report that fatty acid synthase knockdown (FASN) in ECs impedes vessel sprouting by reducing proliferation. Endothelial...
30.
Treps L
J Pathol
. 2018 Jun;
246(1):3-6.
PMID: 29876930
Glioblastoma multiforme (GBM) is a highly vascularized and aggressive brain tumor. Despite aggressive standard care, GBM remains predominantly fatal; hence, new innovative therapies are required. Recent research published in the...