Lucas Treps
Overview
Explore the profile of Lucas Treps including associated specialties, affiliations and a list of published articles.
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Articles
46
Citations
3257
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0
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Recent Articles
11.
Declercq M, Treps L, Bousfia S, Carmeliet P, Witters P
Eur Respir J
. 2021 Aug;
58(2).
PMID: 34385264
No abstract available.
12.
Dumas S, Meta E, Conchinha N, Sokol L, Chen R, Borri M, et al.
STAR Protoc
. 2021 Aug;
2(3):100523.
PMID: 34382011
Endothelial cells (ECs) exhibit phenotypic and functional tissue specificities, critical for studies in the vascular field and beyond. Thus, tissue-specific methods for isolation of highly purified ECs are necessary. Kidney,...
13.
Teuwen L, de Rooij L, Cuypers A, Rohlenova K, Dumas S, Garcia-Caballero M, et al.
Cell Rep
. 2021 Jun;
35(11):109253.
PMID: 34133923
Tumor vessel co-option is poorly understood, yet it is a resistance mechanism against anti-angiogenic therapy (AAT). The heterogeneity of co-opted endothelial cells (ECs) and pericytes, co-opting cancer and myeloid cells...
14.
Sokol L, Geldhof V, Garcia-Caballero M, Conchinha N, Dumas S, Meta E, et al.
STAR Protoc
. 2021 May;
2(2):100489.
PMID: 34007969
Endothelial cells (ECs) from the small intestine, colon, liver, and heart have distinct phenotypes and functional adaptations that are dependent on their physiological environment. Gut ECs adapt to low oxygen,...
15.
Treps L, Declercq M, Bousfia S, Carmeliet P, Witters P
J Cyst Fibros
. 2021 Apr;
20(5):876-880.
PMID: 33858770
The mesenchymal conversion of epithelial cells (EMT) has been suggested as a potential contributor in cystic fibrosis (CF) disease progression. Endothelial cells (EndCs), the cells lining blood vessels, express functional...
16.
Treps L, Faure S, Clere N
Pharmacol Ther
. 2021 Jan;
223:107805.
PMID: 33465401
Tumor cell vasculogenic mimicry (VM), also dubbed vascular mimicry, describes the plasticity of aggressive cancer cells forming de novo vascular networks and is associated with the malignant phenotype and poor...
17.
Declercq M, de Zeeuw P, Conchinha N, Geldhof V, Ramalho A, Garcia-Caballero M, et al.
Eur Respir J
. 2020 Nov;
57(4).
PMID: 33184117
Cystic fibrosis (CF) is a life-threatening disorder characterised by decreased pulmonary mucociliary and pathogen clearance, and an exaggerated inflammatory response leading to progressive lung damage. CF is caused by bi-allelic...
18.
Eelen G, Treps L, Li X, Carmeliet P
Circ Res
. 2020 Aug;
127(2):310-329.
PMID: 32833569
All organisms growing beyond the oxygen diffusion limit critically depend on a functional vasculature for survival. Yet blood vessels are far more than passive, uniform conduits for oxygen and nutrient...
19.
Kara-Terki L, Treps L, Blanquart C, Fradin D
Int J Mol Sci
. 2020 Aug;
21(17).
PMID: 32825667
Extracellular vesicles (EVs), such as exosomes, are critical mediators of intercellular communication between tumor cells and other cells located in the microenvironment but also in more distant sites. Exosomes are...
20.
Taverna F, Goveia J, Karakach T, Khan S, Rohlenova K, Treps L, et al.
Nucleic Acids Res
. 2020 May;
48(W1):W385-W394.
PMID: 32392297
The amount of biological data, generated with (single cell) omics technologies, is rapidly increasing, thereby exacerbating bottlenecks in the data analysis and interpretation of omics experiments. Data mining platforms that...