Lonnie P Wollmuth
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Explore the profile of Lonnie P Wollmuth including associated specialties, affiliations and a list of published articles.
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64
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3566
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Recent Articles
1.
He M, Wollmuth L
J Gen Physiol
. 2024 Nov;
157(1).
PMID: 39576244
NMDA receptors (NMDAR) convert the major excitatory neurotransmitter glutamate into a synaptic signal. A key question is how efficiently the ion channel opens in response to the rapid exposure to...
2.
Zoodsma J, Gomes C, Sirotkin H, Wollmuth L
Methods Mol Biol
. 2024 May;
2799:243-255.
PMID: 38727911
Zebrafish are a powerful system to study brain development and to dissect the activity of complex circuits. One advantage is that they display complex behaviors, including prey capture, learning, responses...
3.
Napoli A, Laderwager S, Zoodsma J, Biju B, Mucollari O, Schubel S, et al.
Sci Rep
. 2024 Feb;
14(1):3395.
PMID: 38336823
Developmental neurogenesis is a tightly regulated spatiotemporal process with its dysregulation implicated in neurodevelopmental disorders. NMDA receptors are glutamate-gated ion channels that are widely expressed in the early nervous system,...
4.
Napoli A, Laderwager S, Zoodsma J, Biju B, Mucollari O, Schubel S, et al.
bioRxiv
. 2023 Oct;
PMID: 37786708
Developmental neurogenesis is a tightly regulated spatiotemporal process with its dysregulation implicated in neurodevelopmental disorders. NMDA receptors are glutamate-gated ion channels that are widely expressed in the early nervous system,...
5.
Moody G, Musco A, Bennett J, Wollmuth L
Neuropharmacology
. 2023 Sep;
240:109703.
PMID: 37689262
The NMDA receptor (NMDAR) is a ubiquitously expressed glutamate-gated ion channel that plays key roles in brain development and function. Not surprisingly, a variety of disease-associated variants have been identified...
6.
Certain N, Gan Q, Bennett J, Hsieh H, Wollmuth L
J Biol Chem
. 2023 Sep;
299(10):105227.
PMID: 37673338
α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) auxiliary subunits are specialized, nontransient binding partners of AMPARs that modulate AMPAR channel gating properties and pharmacology, as well as their biogenesis and trafficking. The most...
7.
8.
Amin J, He M, Prasad R, Leng X, Zhou H, Wollmuth L
Nat Commun
. 2023 Mar;
14(1):1623.
PMID: 36959168
Kinetics of NMDA receptor (NMDAR) ion channel opening and closing contribute to their unique role in synaptic signaling. Agonist binding generates free energy to open a canonical gate at the...
9.
Certain N, Gan Q, Bennett J, Hsieh H, Wollmuth L
bioRxiv
. 2023 Feb;
PMID: 36798164
AMPA receptor (AMPAR) auxiliary subunits are specialized, non-transient binding partners of AMPARs that modulate their ion channel gating properties and pharmacology, as well as their biogenesis and trafficking. The most...
10.
Zoodsma J, Keegan E, Moody G, Bhandiwad A, Napoli A, Burgess H, et al.
Mol Autism
. 2022 Sep;
13(1):38.
PMID: 36138431
Background: Autism spectrum disorder (ASD), like many neurodevelopmental disorders, has complex and varied etiologies. Advances in genome sequencing have identified multiple candidate genes associated with ASD, including dozens of missense...