Lizhi Pang
Overview
Explore the profile of Lizhi Pang including associated specialties, affiliations and a list of published articles.
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22
Citations
333
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Recent Articles
1.
Pang L, Huang Y, Huang-Gao J, Chen P
Trends Cancer
. 2025 Mar;
PMID: 40057434
Proteases play a crucial role in cancer progression and are traditionally known for their protumorigenic role by degrading the extracellular matrix (ECM). Emerging evidence indicates that proteases, such as caspases,...
2.
Liu Y, Wu J, Najem H, Lin Y, Pang L, Khan F, et al.
J Clin Invest
. 2024 Oct;
134(22).
PMID: 39352749
Tumor-associated macrophages and microglia (TAMs) are critical for tumor progression and therapy resistance in glioblastoma (GBM), a type of incurable brain cancer. We previously identified lysyl oxidase (LOX) and olfactomedin...
3.
Pang L, Zhou F, Chen P
Cancer Res
. 2024 Sep;
84(22):3712-3714.
PMID: 39292810
Tumor-associated microglia and macrophages (TAM) make up the largest immune cell population in the glioblastoma (GBM) tumor microenvironment. Given the heterogeneity and plasticity of TAMs in the GBM tumor microenvironment,...
4.
Pang L, Zhou F, Liu Y, Ali H, Khan F, Heimberger A, et al.
J Clin Invest
. 2024 Aug;
134(12).
PMID: 39133578
Although cancer has long been considered a genetic disease, increasing evidence shows that epigenetic aberrations play a crucial role in affecting tumor biology and therapeutic response. The dysregulated epigenome in...
5.
Liu Y, Ali H, Khan F, Pang L, Chen P
Trends Mol Med
. 2024 Mar;
30(5):429-442.
PMID: 38453529
Glioma is a type of aggressive and incurable brain tumor. Patients with glioma are highly resistant to all types of therapies, including immunotherapies. Epigenetic reprogramming is a key molecular hallmark...
6.
Khan F, Lin Y, Ali H, Pang L, Dunterman M, Hsu W, et al.
Nat Commun
. 2024 Mar;
15(1):1987.
PMID: 38443336
Abundant macrophage infiltration and altered tumor metabolism are two key hallmarks of glioblastoma. By screening a cluster of metabolic small-molecule compounds, we show that inhibiting glioblastoma cell glycolysis impairs macrophage...
7.
Khan F, Lin Y, Ali H, Pang L, Dunterman M, Hsu W, et al.
Res Sq
. 2023 Oct;
PMID: 37886538
Abundant macrophage infiltration and altered tumor metabolism are two key hallmarks of glioblastoma. By screening a cluster of metabolic small-molecule compounds, we show that inhibiting glioblastoma cell glycolysis impairs macrophage...
8.
Pang L, Guo S, Khan F, Dunterman M, Ali H, Liu Y, et al.
Cell Rep Med
. 2023 Oct;
4(11):101238.
PMID: 37858339
Glioblastoma (GBM) is a hypoxic and "immune-cold" tumor containing rich stromal signaling molecules and cell populations, such as proteases and immunosuppressive tumor-associated macrophages (TAMs). Here, we seek to profile and...
9.
Pang L, Dunterman M, Guo S, Khan F, Liu Y, Taefi E, et al.
Nat Immunol
. 2023 Sep;
24(10):1654-1670.
PMID: 37667051
Glioblastoma (GBM) tumors consist of multiple cell populations, including self-renewing glioblastoma stem cells (GSCs) and immunosuppressive microglia. Here we identified Kunitz-type protease inhibitor TFPI2 as a critical factor connecting these...
10.
Pang L, Dunterman M, Xuan W, Gonzalez A, Lin Y, Hsu W, et al.
Cell Rep
. 2023 Feb;
42(2):112127.
PMID: 36795563
Glioblastoma (GBM) is one of the most aggressive tumors in the adult central nervous system. We previously revealed that circadian regulation of glioma stem cells (GSCs) affects GBM hallmarks of...