Linan Ha
Overview
Explore the profile of Linan Ha including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
352
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0
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Recent Articles
1.
Amiri-Kordestani L, Blumenthal G, Xu Q, Zhang L, Tang S, Ha L, et al.
Clin Cancer Res
. 2014 Jun;
20(17):4436-41.
PMID: 24879797
On February 22, 2013, the FDA licensed ado-trastuzumab emtansine (Kadcyla; Genentech, Inc.) for use as a single agent for the treatment of patients with human epidermal growth factor receptor 2...
2.
King K, Ha L, Camilli T, Weinberg W
J Skin Cancer
. 2013 May;
2013:632028.
PMID: 23710361
Mouse models have informed us that p63 is critical for normal epidermal development and homeostasis. The p53/p63/p73 family is expressed as multiple protein isoforms due to a combination of alternative...
3.
Ha L, Ponnamperuma R, Jay S, Ricci M, Weinberg W
PLoS One
. 2011 Jul;
6(7):e21877.
PMID: 21789189
p63 is critical for squamous epithelial development, and elevated levels of the ΔNp63α isoform are seen in squamous cell cancers of various organ sites. However, significant controversy exists regarding the...
4.
Ha L, Merlino G, Sviderskaya E
Cell Cycle
. 2008 Jul;
7(13):1944-8.
PMID: 18604170
Although melanoma ultimately progresses to a highly aggressive and metastatic disease that is typically resistant to currently available therapy, it often begins as a benign nevus consisting of a clonal...
5.
Ha L, Ichikawa T, Anver M, Dickins R, Lowe S, Sharpless N, et al.
Proc Natl Acad Sci U S A
. 2007 Jun;
104(26):10968-73.
PMID: 17576930
Inactivation of the p53 pathway represents the most common molecular defect of human cancer. But in the setting of melanoma, a highly aggressive and invariably fatal malignancy in its advanced...
6.
Ha L, Noonan F, De Fabo E, Merlino G
J Investig Dermatol Symp Proc
. 2005 Dec;
10(2):86-8.
PMID: 16358815
No abstract available.
7.
Pritchard D, Ceryak S, Ramsey K, OBrien T, Ha L, Fornsaglio J, et al.
Mol Cell Biochem
. 2005 Nov;
279(1-2):169-81.
PMID: 16283527
Certain hexavalent chromium [Cr(VI)] compounds are known genotoxic respiratory carcinogens, which induce apoptosis as a predominant mode of cell death. Selection of cells that are resistant to apoptosis may be...
8.
Ha L, Ceryak S, Patierno S
Carcinogenesis
. 2004 Jul;
25(11):2265-74.
PMID: 15284180
Certain hexavalent chromium [Cr(VI)] compounds are implicated as occupational respiratory carcinogens. Cr(VI) induces a broad spectrum of DNA damage, but Cr(VI)-induced DNA double-strand breaks (DSBs) have not been reported. Previously...
9.
Ha L, Ceryak S, Patierno S
J Biol Chem
. 2003 Mar;
278(20):17885-94.
PMID: 12637545
The ataxia telangiectasia mutated (ATM) protein plays a central role in early stages of DNA double strand break (DSB) detection and controls cellular responses to this damage. Although hypersensitive to...
10.
Vilcheck S, OBrien T, Pritchard D, Ha L, Ceryak S, Fornsaglio J, et al.
Environ Health Perspect
. 2002 Nov;
110 Suppl 5:773-7.
PMID: 12426130
Fanconi anemia (FA) is an autosomal recessive disorder characterized by diverse developmental abnormalities, progressive bone marrow failure, and a markedly increased incidence of malignancy. FA cells are hypersensitive to DNA...