Susan Ceryak
Overview
Explore the profile of Susan Ceryak including associated specialties, affiliations and a list of published articles.
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26
Citations
499
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Recent Articles
1.
Nickens K, Wikstrom J, Shirihai O, Patierno S, Ceryak S
Mitochondrion
. 2013 Oct;
13(6):662-7.
PMID: 24075934
Apoptosis-resistance and metabolic imbalances are prominent features of cancer cells. We have recently reported on populations of human fibroblasts that exhibit resistance to mitochondrial-mediated apoptosis, acquired as a result of...
2.
Kost G, Patierno S, Wise S, Holmes A, Wise Sr J, Ceryak S
Mutat Res
. 2012 May;
735(1-2):51-5.
PMID: 22583656
Inappropriate survival signaling after DNA damage may facilitate clonal expansion of genetically compromised cells, and it is known that protein tyrosine phosphatase (PTP) inhibitors activate key survival pathways. In this...
3.
Nickens K, Han Y, Shandilya H, Larrimore A, Gerard G, Kaldjian E, et al.
Biochim Biophys Acta
. 2011 Nov;
1823(2):264-72.
PMID: 22057391
Acquisition of death-resistance is critical in the evolution of neoplasia. Our aim was to model the early stages of carcinogenesis by examining intracellular alterations in cells that have acquired apoptosis-resistance...
4.
Krilov L, Nguyen A, Miyazaki T, Unson C, Williams R, Lee N, et al.
Exp Cell Res
. 2011 Oct;
317(20):2981-94.
PMID: 22001118
Glucagon levels are elevated in diabetes and some liver diseases. Increased glucagon secretion leads to abnormal stimulation of glucagon receptors (GRs) and consequent elevated glucose production in the liver. Blocking...
5.
Nickens K, Patierno S, Ceryak S
Chem Biol Interact
. 2010 May;
188(2):276-88.
PMID: 20430016
Certain forms of hexavalent chromium [Cr(VI)] are known respiratory carcinogens that induce a broad spectrum of DNA damage. Cr(VI)-carcinogenesis may be initiated or promoted through several mechanistic processes including, the...
6.
Chun G, Bae D, Nickens K, OBrien T, Patierno S, Ceryak S
Carcinogenesis
. 2010 Jan;
31(5):785-93.
PMID: 20089605
Polo-like kinase 1 (Plk1) is a key regulator of mitosis. Aberrant Plk1 activity is found in tumors, but little is known regarding its role in the DNA damage response of...
7.
Bae D, Ceryak S
Biochem Biophys Res Commun
. 2009 May;
385(4):523-7.
PMID: 19465001
Biological roles of ERK and MEK in signal transduction have been controversial. The aim of the current study was to determine the role of ERK1/2 in signaling through the ERK-MAPK...
8.
Lal M, Bae D, Camilli T, Patierno S, Ceryak S
Cell Cycle
. 2009 Apr;
8(10):1589-602.
PMID: 19377290
Certain forms of hexavalent chromium [Cr(VI)] are human carcinogens. Our recent work has shown that a broad range protein tyrosine phosphatase (PTP) inhibitor, sodium orthovanadate (SOV), abrogated both Cr(VI)-induced growth...
9.
Bae D, Camilli T, Ha N, Ceryak S
Cell Signal
. 2009 Jan;
21(5):727-36.
PMID: 19167484
Our recent studies showed that maintenance of protein tyrosine phosphorylation by PTP inhibition enhanced cell growth, clonogenic survival, and mutagenesis after a single low-level Cr(VI) exposure, thereby suggesting that tyrosine...
10.
Bae D, Camilli T, Chun G, Lal M, Wright K, OBrien T, et al.
Mutat Res
. 2008 Nov;
660(1-2):40-6.
PMID: 19013184
Although the consequences of genotoxic injury include cell cycle arrest and apoptosis, cell survival responses after genotoxic injury can produce intrinsic death-resistance and contribute to the development of a transformed...