Lidija Covic
Overview
Explore the profile of Lidija Covic including associated specialties, affiliations and a list of published articles.
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53
Citations
2248
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Recent Articles
1.
Fletcher E, Ngwenyama N, Nguyen N, Turner S, Covic L, Alcaide P, et al.
Circ Heart Fail
. 2023 Jul;
16(10):e010621.
PMID: 37477012
Background: PAR1 (protease-activated receptor-1) contributes to acute thrombosis, but it is not clear whether the receptor is involved in deleterious inflammatory and profibrotic processes in heart failure. Here, we employ...
2.
Abdelmalek M, Covic L, Kuliopulos A
Hepatology
. 2023 Mar;
77(5):E111-E112.
PMID: 36869845
No abstract available.
3.
Shearer A, Wang Y, Fletcher E, Rana R, Michael E, Nguyen N, et al.
Hepatology
. 2022 May;
76(6):1778-1793.
PMID: 35603482
Background And Aims: Insulin resistance and poor glycemic control are key drivers of the development of NAFLD and have recently been shown to be associated with fibrosis progression in NASH....
4.
Mithila F, Schwake C, Fang C, Merrill-Skoloff G, Covic L, Fritz D, et al.
Thromb Res
. 2022 Feb;
211:123-126.
PMID: 35149397
No abstract available.
5.
Michael E, Covic L, Kuliopulos A
Methods Mol Biol
. 2021 Nov;
2383:307-333.
PMID: 34766299
Pepducins are lipidated peptides that target the intracellular loops of G protein-coupled receptors (GPCRs) in order to modulate transmembrane signaling to internally located effectors. With a wide array of potential...
6.
Lee J, Ekambaram P, Carleton N, Hu D, Klei L, Cai Z, et al.
Mol Cancer Res
. 2021 Nov;
20(3):373-386.
PMID: 34753803
Implications: This study nominates a GPCR/MALT1 signaling axis as a pathway that can be pharmaceutically targeted to abrogate EMT and metastatic progression in TNBC, an aggressive form of breast cancer...
7.
Fletcher E, Wang Y, Flynn L, Turner S, Rade J, Kimmelstiel C, et al.
Arterioscler Thromb Vasc Biol
. 2021 Mar;
41(5):e265-e279.
PMID: 33761760
[Figure: see text].
8.
Van Doren L, Nguyen N, Garzia C, Fletcher E, Stevenson R, Jaramillo D, et al.
Arterioscler Thromb Vasc Biol
. 2020 Dec;
41(1):e33-e45.
PMID: 33267659
Objective: 12-LOX (12-lipoxygenase) produces a number of bioactive lipids including 12(S)-HETE that are involved in inflammation and platelet reactivity. The GPR31 (G-protein-coupled receptor 31) is the proposed receptor of 12(S)-HETE;...
9.
Kuliopulos A, Gurbel P, Rade J, Kimmelstiel C, Turner S, Bliden K, et al.
Arterioscler Thromb Vasc Biol
. 2020 Oct;
40(12):2990-3003.
PMID: 33028101
Objective: Arterial thrombosis leading to ischemic injury worsens the prognosis of many patients with cardiovascular disease. PZ-128 is a first-in-class pepducin that reversibly inhibits PAR1 (protease-activated receptor 1) on platelets...
10.
Rana R, Shearer A, Fletcher E, Nguyen N, Guha S, Cox D, et al.
Mol Metab
. 2019 Nov;
29:99-113.
PMID: 31668396
Objective: Increases in hepatic and plasma cholesterol occur in patients with nonalcoholic fatty liver disease (NAFLD), although the reason for this is not well understood. We investigated whether Protease-Activated Receptor...