Leonardo L G Ferreira
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Explore the profile of Leonardo L G Ferreira including associated specialties, affiliations and a list of published articles.
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40
Citations
379
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Recent Articles
1.
Mollo M, Cambiaso M, Ferreira L, Kilimciler N, Bisceglia J, Andricopulo A, et al.
Bioorg Chem
. 2024 Dec;
154():108083.
PMID: 39721144
This work describes the synthesis and biological evaluation of hitherto unknown N-arylspermidine derivatives 3. Compounds 3 were efficiently prepared from cyclic amidines through a novel synthetic approach comprising alkylation with...
2.
da Silva Oliveira D, Sousa Silva N, Jacques Dit Lapierre T, de Souza S, Ferreira Brito N, Cassiano Martinho A, et al.
Chem Biodivers
. 2024 Sep;
22(2):e202402100.
PMID: 39327235
Microorganisms can induce diseases with significant clinical implications for human health. Multidrug-resistant microorganisms have been on the rise worldwide over the past few decades, and no new antibiotics have been...
3.
Valli M, Doring T, Marx E, Ferreira L, Medina-Franco J, Andricopulo A
Biomolecules
. 2024 Aug;
14(8).
PMID: 39199420
The development of new treatments for neglected tropical diseases (NTDs) remains a major challenge in the 21st century. In most cases, the available drugs are obsolete and have limitations in...
4.
Slafer B, Dessoy M, de Oliveira R, Mollo M, Lee E, Matheeussen A, et al.
ACS Omega
. 2024 May;
9(20):22360-22370.
PMID: 38799347
Chagas disease (CD) is a parasitic neglected tropical disease (NTD) caused by the protozoan that affects 6 million people worldwide, often resulting in financial burden, morbidity, and mortality in endemic...
5.
Jacques Dit Lapierre T, Nascimento Farago D, Cruz M, Resende D, de Oliveira A, Dos Santos B, et al.
Chem Biol Drug Des
. 2024 Apr;
103(4):e14525.
PMID: 38627214
An early exploration of the benzothiazole class against two kinetoplastid parasites, Leishmania infantum and Trypanosoma cruzi, has been performed after the identification of a benzothiazole derivative as a suitable antileishmanial...
6.
Machado V, Cenci A, Teixeira K, Sens L, Tizziani T, Nunes R, et al.
RSC Med Chem
. 2022 Dec;
13(12):1644-1656.
PMID: 36561075
Alzheimer's disease (AD) is a neurodegenerative disease that is characterized as the main dementia in the elderly. Eighteen pyrazolines were synthesized and evaluated for their inhibitory effects against acetylcholinesterase (AChE)...
7.
Teles H, Valli M, Ferreira L, Andricopulo A
J Phys Chem B
. 2022 Dec;
126(51):10834-10843.
PMID: 36534784
Visceral leishmaniasis is a neglected tropical disease (NTD) caused by and that is lethal in cases of nontreatment. The treatments are limited by serious drawbacks involving safety, resistance, stability, and...
8.
de Oliveira Rezende Junior C, Martinez P, Ferreira R, Koovits P, Miranda Soares B, Ferreira L, et al.
Eur J Med Chem
. 2022 Dec;
246:114925.
PMID: 36459758
Chagas disease is a neglected tropical disease caused by Trypanosoma cruzi. Because current treatments present several limitations, including long duration, variable efficacy and serious side effects, there is an urgent...
9.
Chipoline I, Brasil B, Neto J, Valli M, Krogh R, Cenci A, et al.
Eur J Med Chem
. 2022 Sep;
243:114687.
PMID: 36057237
Chagas Disease is caused by the protozoan Trypanosoma cruzi and is considered a tropical neglected disease by the World Health Organization (WHO). The main drugs used in the therapy of...
10.
Teles H, Ferreira L, Valli M, Coelho F, Andricopulo A
Int J Mol Sci
. 2022 Aug;
23(16).
PMID: 36012163
Leishmaniasis is a neglected tropical disease that kills more than 20,000 people each year. The chemotherapy available for the treatment of the disease is limited, and novel approaches to discover...