Adriano D Andricopulo
Overview
Explore the profile of Adriano D Andricopulo including associated specialties, affiliations and a list of published articles.
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133
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1843
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Recent Articles
1.
Umehara E, Cajas R, Conceicao G, Antar G, Andricopulo A, de Moraes J, et al.
Molecules
. 2025 Jan;
30(2).
PMID: 39860137
In the present study, the hexane extract from branches of (Winteraceae) displayed potent activity against parasites (100% mortality of the worms at 200 μg/mL). Bioactivity-guided fractionation afforded, in addition to...
2.
Mollo M, Cambiaso M, Ferreira L, Kilimciler N, Bisceglia J, Andricopulo A, et al.
Bioorg Chem
. 2024 Dec;
154():108083.
PMID: 39721144
This work describes the synthesis and biological evaluation of hitherto unknown N-arylspermidine derivatives 3. Compounds 3 were efficiently prepared from cyclic amidines through a novel synthetic approach comprising alkylation with...
3.
Gomez-Garcia A, Acuna Jimenez D, Zamora W, Barazorda-Ccahuana H, Chavez-Fumagalli M, Valli M, et al.
J Chem Inf Model
. 2024 Nov;
64(22):8495-8509.
PMID: 39503579
Natural product (NP) databases are crucial tools in computer-aided drug design (CADD). Over the past decade, there has been a worldwide effort to assemble information regarding natural products (NPs) isolated...
4.
da Silva Oliveira D, Sousa Silva N, Jacques Dit Lapierre T, de Souza S, Ferreira Brito N, Cassiano Martinho A, et al.
Chem Biodivers
. 2024 Sep;
22(2):e202402100.
PMID: 39327235
Microorganisms can induce diseases with significant clinical implications for human health. Multidrug-resistant microorganisms have been on the rise worldwide over the past few decades, and no new antibiotics have been...
5.
Valli M, Doring T, Marx E, Ferreira L, Medina-Franco J, Andricopulo A
Biomolecules
. 2024 Aug;
14(8).
PMID: 39199420
The development of new treatments for neglected tropical diseases (NTDs) remains a major challenge in the 21st century. In most cases, the available drugs are obsolete and have limitations in...
6.
Dobrachinski L, Ferreira L, Cirino M, Andrade-de-Siqueira A, Mafud A, Mascarenhas Y, et al.
Future Med Chem
. 2024 Jul;
16(17):1791-1799.
PMID: 39072451
To identify potential antischistosomal agents through 3D pharmacophore-based virtual screening of US FDA approved drugs. A comprehensive virtual screening was conducted on a dataset of 10,000 FDA approved drugs, employing...
7.
Gomez-Garcia A, Prinz A, Acuna Jimenez D, Zamora W, Barazorda-Ccahuana H, Chavez-Fumagalli M, et al.
Mol Inform
. 2024 Jul;
43(7):e202400052.
PMID: 38994633
Compound databases of natural products play a crucial role in drug discovery and development projects and have implications in other areas, such as food chemical research, ecology and metabolomics. Recently,...
8.
Espinoza-Chavez R, de Oliveira Rezende Junior C, De Souza M, Consolin Chelucci R, Michelan-Duarte S, Krogh R, et al.
ChemMedChem
. 2024 Jun;
19(20):e202400293.
PMID: 38924252
This study introduces further insights from the hit-to-lead optimization process involving a series of benzimidazole derivatives acting as inhibitors of the cruzain enzyme, which targets Trypanosoma cruzi, the causative parasite...
9.
Slafer B, Dessoy M, de Oliveira R, Mollo M, Lee E, Matheeussen A, et al.
ACS Omega
. 2024 May;
9(20):22360-22370.
PMID: 38799347
Chagas disease (CD) is a parasitic neglected tropical disease (NTD) caused by the protozoan that affects 6 million people worldwide, often resulting in financial burden, morbidity, and mortality in endemic...
10.
Jacques Dit Lapierre T, Nascimento Farago D, Cruz M, Resende D, de Oliveira A, Dos Santos B, et al.
Chem Biol Drug Des
. 2024 Apr;
103(4):e14525.
PMID: 38627214
An early exploration of the benzothiazole class against two kinetoplastid parasites, Leishmania infantum and Trypanosoma cruzi, has been performed after the identification of a benzothiazole derivative as a suitable antileishmanial...