Laura E Ritchey
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Explore the profile of Laura E Ritchey including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
308
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Recent Articles
1.
Jayasinghe O, Ritchey L, Breil T, Newman P, Yakhnin H, Babitzke P
Nucleic Acids Res
. 2024 Nov;
52(21):12945-12960.
PMID: 39494516
Transcription by RNA polymerase is punctuated by transient pausing events. Pausing provides time for RNA folding and binding of regulatory factors to the paused elongation complex. We previously identified 1600...
2.
Ritchey L, Tack D, Yakhnin H, Jolley E, Assmann S, Bevilacqua P, et al.
RNA
. 2020 Jul;
26(10):1431-1447.
PMID: 32611709
RNA structure influences numerous processes in all organisms. In bacteria, these processes include transcription termination and attenuation, small RNA and protein binding, translation initiation, and mRNA stability, and can be...
3.
Waldron J, Tack D, Ritchey L, Gillen S, Wilczynska A, Turro E, et al.
Genome Biol
. 2020 Jan;
20(1):300.
PMID: 31888698
Background: The RNA helicase eIF4A1 is a key component of the translation initiation machinery and is required for the translation of many pro-oncogenic mRNAs. There is increasing interest in targeting...
4.
Ritchey L, Su Z, Assmann S, Bevilacqua P
Methods Mol Biol
. 2019 Apr;
1933:305-341.
PMID: 30945195
In vivo genome-wide RNA structure probing provides a global view of RNA structure as it occurs in the cell and can assist in elucidating important functional aspects of RNA structure....
5.
Su Z, Tang Y, Ritchey L, Tack D, Zhu M, Bevilacqua P, et al.
Proc Natl Acad Sci U S A
. 2018 Nov;
115(48):12170-12175.
PMID: 30413617
The heat shock response is crucial for organism survival in natural environments. RNA structure is known to influence numerous processes related to gene expression, but there have been few studies...
6.
Tack D, Tang Y, Ritchey L, Assmann S, Bevilacqua P
Methods
. 2018 Feb;
143:12-15.
PMID: 29410279
The secondary structure of an RNA is often implicit to its function. Recently, various high-throughput RNA structure probing techniques have been developed to elucidate important RNA structure-function relationships genome-wide. These...
7.
Mitchell 3rd D, Ritchey L, Park H, Babitzke P, Assmann S, Bevilacqua P
RNA
. 2017 Oct;
24(1):114-124.
PMID: 29030489
Elucidation of the folded structures that RNA forms in vivo is vital to understanding its functions. Chemical reagents that modify the Watson-Crick (WC) face of unprotected nucleobases are particularly useful...
8.
Ritchey L, Su Z, Tang Y, Tack D, Assmann S, Bevilacqua P
Nucleic Acids Res
. 2017 Jun;
45(14):e135.
PMID: 28637286
RNA serves many functions in biology such as splicing, temperature sensing, and innate immunity. These functions are often determined by the structure of RNA. There is thus a pressing need...
9.
Bingaman J, Frankel E, Hull C, Leamy K, Messina K, Mitchell 3rd D, et al.
RNA
. 2016 Nov;
22(12):1929-1930.
PMID: 27852929
Gel electrophoresis and subsequent imaging using phosphorimagers is one of the most important and widely used techniques in RNA and DNA analysis. Radiolabeling nucleic acids with P and detecting bands...
10.
Bevilacqua P, Ritchey L, Su Z, Assmann S
Annu Rev Genet
. 2016 Sep;
50:235-266.
PMID: 27648642
Single-stranded RNA molecules fold into extraordinarily complicated secondary and tertiary structures as a result of intramolecular base pairing. In vivo, these RNA structures are not static. Instead, they are remodeled...