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Kiyotsugu Yoshida

Explore the profile of Kiyotsugu Yoshida including associated specialties, affiliations and a list of published articles. Areas
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Articles 90
Citations 3199
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Recent Articles
1.
Ueda K, Oikawa T, Yamada K, Tsubota A, Saeki C, Katagiri K, et al.
Biochem Biophys Res Commun . 2025 Feb; 751:151431. PMID: 39908908
Protein kinase C delta (PKCδ) is a leaderless protein generally localized in the cytoplasm and nucleus; however, its extracellular unconventional protein secretion occurs exclusively in hepatocellular carcinoma (HCC) cells (but...
2.
Yoshida S, Yoshida K
Anat Sci Int . 2024 Nov; 100(2):143-154. PMID: 39576500
The Hedgehog (Hh) signaling pathway is critical for regulating cell growth, survival, fate determination, and the overall patterning of both vertebrate and invertebrate body plans. Aberrations in Hh signaling are...
3.
Oikawa T, Yamada K, Tsubota A, Saeki C, Tago N, Nakagawa C, et al.
Gastro Hep Adv . 2024 Aug; 2(1):83-95. PMID: 39130149
Backgrounds And Aims: Hepatocellular carcinoma (HCC) is the most common cancer with a poor prognosis. Identification of an alternative biomarker that can detect early-stage and conventional tumor marker-negative HCC is...
4.
Yoshida S, Tsuneoka Y, Tsukada T, Nakakura T, Kawamura A, Kai W, et al.
Endocrinology . 2024 Jul; 165(8). PMID: 39001875
The functional maturation of the pituitary gland requires adequate cell differentiation and vascular network formation. Although spatiotemporal signaling and transcription factors are known to govern pituitary development, the involvement of...
5.
Yoshida S, Kawamura A, Aoki K, Wiriyasermkul P, Sugimoto S, Tomiyoshi J, et al.
Proc Natl Acad Sci U S A . 2024 Jul; 121(28):e2320070121. PMID: 38968120
Hedgehog (Hh) signaling, an evolutionarily conserved pathway, plays an essential role in development and tumorigenesis, making it a promising drug target. Multiple negative regulators are known to govern Hh signaling;...
6.
Kawamura A, Yoshida S, Yoshida K
Histol Histopathol . 2024 Apr; 39(11):1427-1434. PMID: 38656683
To maintain microenvironmental and cellular homeostasis, cells respond to multiple stresses by activating characteristic cellular mechanisms consisting of receptors, signal transducers, and effectors. Dysfunction of these mechanisms can trigger multiple...
7.
Harada E, Yoshida S, Imaizumi Y, Kawamura A, Ohtsuka T, Yoshida K
Biochim Biophys Acta Gen Subj . 2024 Mar; 1868(6):130600. PMID: 38508285
Objectives: Lung cancer is a leading cause of cancer-related mortality and remains one of the most poorly prognosed disease worldwide. Therefore, it is necessary to identify novel molecular markers with...
8.
Kamii Y, Hayashizaki K, Kanno T, Chiba A, Ikegami T, Saito M, et al.
Proc Natl Acad Sci U S A . 2024 Feb; 121(9):e2313964121. PMID: 38394242
Invariant natural killer T (iNKT) cells are innate-like T lymphocytes that express an invariant T cell receptor α chain and contribute to bridging innate and acquired immunity with rapid production...
9.
Nakagawa C, Oikawa T, Yamada K, Tsubota A, Saeki C, Katagiri K, et al.
Biomarkers . 2024 Feb; 29(2):55-67. PMID: 38361436
Background: The conventional markers for hepatocellular carcinoma (HCC), α-fetoprotein (AFP) and des-γ-carboxy prothrombin (DCP), have several limitations; both have low sensitivity in patients with early-stage HCC; low sensitivity for AFP...
10.
Mochimaru Y, Yoshida K
Curr Issues Mol Biol . 2023 Oct; 45(10):8539-8551. PMID: 37886981
The dual-specificity tyrosine phosphorylation-regulated kinase 2 (DYRK2) regulates the induction of apoptosis and DNA repair, metastasis inhibition, cell cycle G1/S transition, protein scaffold stability for E3 ligase complexes, and embryogenesis....